Totani Nagao, Araki Yurika, Tateishi Sayuri
Faculty of Nutrition, Kobe-Gakuin University, Kobe, Japan.
J Oleo Sci. 2010;59(3):115-20. doi: 10.5650/jos.59.115.
It has been reported that oil heated with vegetable protein under reduced pressure, followed by filtration (soy oil), decreased body, liver and retroperitoneal fat tissue weights and serum triacylglycerol levels in Wistar rats. In order to clarify the mechanism of these weight-loss promoting effects, gastrointestinal tract content transfer was traced. Fasted 10-week-old rats were fed a slurry containing AIN93G without fat, Cr(2)O(3) (marker), and 7 wt% soy oil or fresh oil (control) and sacrificed at 20, 60, 120, or 360 min; then, blood, stomach, small intestine, cecum, colon and feces were collected. The results indicated that the content transferred faster from stomach to small intestine in the soy oil group than in the control group. At 60 min after the ingestion of diet, an increased serum triacylglycerol level was found in the soy oil group. In addition, fecal excretion in the soy oil group was significantly higher 120 min after the administration than in the control group, suggesting that soy oil stimulated peristalsis of the colon and that colon contents (food ingested before administration) were actively excreted.
据报道，在减压条件下用植物蛋白加热油，随后过滤（大豆油），可降低Wistar大鼠的体重、肝脏和腹膜后脂肪组织重量以及血清三酰甘油水平。为了阐明这些促进减肥作用的机制，对胃肠道内容物转移进行了追踪。将禁食的10周龄大鼠喂食含有不含脂肪的AIN93G、Cr(2)O(3)（标记物）和7 wt%大豆油或新鲜油（对照）的浆液，并在20、60、120或360分钟时处死；然后收集血液、胃、小肠、盲肠、结肠和粪便。结果表明，大豆油组中内容物从胃转移到小肠的速度比对照组快。在摄入饮食后60分钟，大豆油组的血清三酰甘油水平升高。此外，大豆油组给药后120分钟的粪便排泄量显著高于对照组，表明大豆油刺激了结肠蠕动，并且结肠内容物（给药前摄入的食物）被积极排泄。
