Spinal Cord Injury Center, VA Palo Alto Health Care System, Stanford University, Palo Alto, CA 94304, USA.
Spinal Cord. 2010 Aug;48(8):639-44. doi: 10.1038/sc.2009.196. Epub 2010 Feb 2.
Prospective comparison of spinal cord injured (SCI) subjects and ambulatory subjects.
To determine the effects of the presence and level of SCI on heart rate recovery (HRR).
Outpatient SCI center.
HRR was determined in 63 SCI subjects (26 with tetraplegia, 22 with high-level paraplegia, 15 with low-level paraplegia) and 26 ambulatory subjects. To adjust for differences in heart rate reserve between groups (HR peak minus HR rest), HRR was also 'normalized' to a range of 1 at peak heart rate and to 0 at 8 min, and the shapes of HRR curves were compared.
Although absolute HRR was similar between high- and low-level paraplegia, it was significantly more rapid in participants with paraplegia at 2, 5 and 8 min after exercise than in those with tetraplegia (39+/-14 vs 29+/-14 b.p.m., P<0.05; 51+/-14 vs 33+/-16 b.p.m., P<0.01 and 52+/-16 vs 36+/-17 b.p.m., P<0.01, respectively). HRR among ambulatory subjects was more rapid than among those with tetraplegia at all time points in recovery. However, when normalized for heart rate reserve, HRR was significantly more rapid in tetraplegic subjects (P<0.001 vs paraplegia and ambulatory subjects).
In SCI, HRR is strongly associated with the peak exercise level and peak heart rate achieved during exercise testing.
对脊髓损伤（SCI）患者和非卧床患者进行前瞻性比较。
确定 SCI 的存在和水平对心率恢复（HRR）的影响。
门诊 SCI 中心。
在 63 名 SCI 患者（26 名四肢瘫痪，22 名高位截瘫，15 名低位截瘫）和 26 名非卧床患者中确定 HRR。为了调整组间心率储备的差异（HR 峰值减去 HR 休息），HRR 也“归一化”到心率峰值范围为 1，心率 8 分钟时为 0，并比较 HRR 曲线的形状。
尽管高水平和低水平截瘫之间的绝对 HRR 相似，但在运动后 2、5 和 8 分钟时，截瘫患者的 HRR 明显快于四肢瘫痪患者（39+/-14 比 29+/-14 b.p.m.，P<0.05；51+/-14 比 33+/-16 b.p.m.，P<0.01 和 52+/-16 比 36+/-17 b.p.m.，P<0.01）。在恢复期间，非卧床患者的 HRR 比四肢瘫痪患者的 HRR 快。然而，当按心率储备归一化时，四肢瘫痪患者的 HRR 明显更快（P<0.001 比截瘫和非卧床患者）。
在 SCI 中，HRR 与运动测试期间达到的最大运动水平和最大心率密切相关。
