Adjei G O, Darkwah A K, Goka B Q, Bart-Plange C, Alifrangis M L, Kurtzhals J A L, Rodrigues O P
Centre for Tropical Clinical Pharmacology & Therapeutics, University of Ghana Medical School, Accra, Ghana.
Ghana Med J. 2009 Sep;43(3):99-106. doi: 10.4314/gmj.v43i3.55324.
There is little information on sociocultural and contextual factors that may influence attitudes of patients to new treatments, such as artemisinin combination therapies (ACT).
Semi-structured questionnaires and focus group discussions were used to assess views of parents of children with uncomplicated malaria treated with ACT in a low socio-economic area in Accra, Ghana.
The majority of parents reported a favourable experience, in terms of perceived i) rapidity of symptom resolution, compared to their previous experience of other therapies for childhood malaria, or ii) when their experience was compared that of parents of children treated with monotherapy. The parents of children treated with ACT were more willing to pay for the treatment, or adhere to the full treatment course. The explanations given for adherence were consistent with conventional biomedical explanations. Although care-seeking practices for childhood malaria were considered appropriate, perceived or real barriers to accessible health care were also important factors in the decision to seek treatment. Household dynamics and perceived inequities at the care-provider-patient interface were identified as having potential negative impact on care-seeking practices and adherence.
Health education messages aimed at improving the response to childhood febrile illness should include other strategic stakeholders, such as decision-makers at the household level. The effectiveness and implementation success of the ACT policy could be enhanced by highlighting and reinforcing messages intrinsic to these regimens. Integrating the views of caretakers during the clinical encounter was validated as an empowerment tool that could aid in the appropriate responses to childhood illness.
关于可能影响患者对新疗法(如青蒿素联合疗法[ACT])态度的社会文化和背景因素的信息很少。
采用半结构化问卷和焦点小组讨论,评估在加纳阿克拉一个社会经济水平较低地区接受ACT治疗的单纯性疟疾患儿家长的看法。
大多数家长报告了良好的体验,这体现在:i)与他们之前治疗儿童疟疾的其他疗法相比,症状缓解速度更快;ii)与接受单一疗法治疗的儿童的家长的体验相比。接受ACT治疗的儿童的家长更愿意为治疗付费,或坚持完成整个疗程。给出的坚持治疗的理由与传统生物医学解释一致。虽然儿童疟疾的就医行为被认为是恰当的,但可及医疗服务存在的感知或实际障碍也是决定寻求治疗的重要因素。家庭动态以及在医疗服务提供者与患者界面存在的感知到的不公平被认为对就医行为和坚持治疗有潜在负面影响。
旨在改善对儿童发热性疾病反应的健康教育信息应纳入其他战略利益相关者,如家庭层面的决策者。通过强调和强化这些治疗方案固有的信息,可以提高ACT政策的有效性和实施成功率。在临床诊疗过程中整合照顾者的观点被证实是一种赋权工具,有助于对儿童疾病做出恰当反应。