[大脑发育与性腺激素]
[Brain development and gonadal hormones].
作者信息
Arai Y
机构信息
Department of Anatomy, Juntendo University School of Medicine, Tokyo.
出版信息
No To Hattatsu. 1991 Mar;23(2):129-35.
Gonadal steroids play an important role in exerting functional sexual differentiation of the brain. Recently there has been accumulating evidence that gonadal steroids regulate neuron number, axonal and dendritic growth and synapse formation in the neuronal system containing sex steroid receptors. These provide morphological bases for sexually dimorphic function of the brain. Other than in the developmental process, gonadal steroids are found to take care of neuronal plasticity in certain brain areas.
性腺类固醇在大脑功能性别的分化过程中发挥着重要作用。最近，越来越多的证据表明，性腺类固醇在含有性类固醇受体的神经系统中调节神经元数量、轴突和树突的生长以及突触的形成。这些为大脑的性别二态性功能提供了形态学基础。除了在发育过程中，性腺类固醇还被发现对某些脑区的神经元可塑性有影响。
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