Environmental Epidemiology Research Centre, Biomedical Research Park, 08003 Barcelona, Spain.
Eur J Nutr. 2010 Sep;49(6):357-64. doi: 10.1007/s00394-010-0093-z. Epub 2010 Feb 4.
To analyse the association of trans fatty acid (TFA) consumption with the risk of type 2 diabetes and lifestyle in a South European population.
Data were obtained from two population-based cross-sectional surveys conducted in Gerona (Spain) in 2000 and 2005. The present analysis included 7,774 free-living Spanish men and women aged 35-74 years. Diet was assessed by a validated food frequency questionnaire. Fasting blood sugar was measured and history of diabetes recorded.
trans Fatty acid intake was relatively low in our study population (1.5 g d(-1) for women and 1.8 g d(-1) for men). Multiple logistic regression analysis revealed a null association between TFA intake and risk of type 2 diabetes in men and women. Total energy intake, alcohol consumption and the prevalence of smoking increased across quartiles of TFA intake. An inverse association was found between TFA intake and the consumption of vegetables, fruit, fish, legumes, white bread and olive oil in both genders (p < 0.001) after adjusting for energy intake. In contrast, intakes of meat, sausages and pastry products increased across quartiles of TFA intake in both genders (p < 0.001).
trans Fatty acid intake was not associated with a higher risk of type 2 diabetes. Higher TFA intake was associated with less healthy lifestyle and dietary habits in both sexes.
分析在南欧人群中,反式脂肪酸(TFA)的摄入与 2 型糖尿病风险和生活方式之间的关联。
数据来自于 2000 年和 2005 年在西班牙赫罗纳进行的两项基于人群的横断面调查。本分析包括 7774 名年龄在 35-74 岁的自由生活的西班牙男女。饮食通过经过验证的食物频率问卷进行评估。测量空腹血糖并记录糖尿病史。
在我们的研究人群中,反式脂肪酸的摄入量相对较低(女性 1.5 克/天,男性 1.8 克/天)。多变量逻辑回归分析显示,TFA 摄入量与男性和女性 2 型糖尿病风险之间不存在关联。总能量摄入、饮酒量和吸烟率随着 TFA 摄入量的四分位增加而增加。在调整能量摄入后,TFA 摄入量与男女两性蔬菜、水果、鱼类、豆类、白面包和橄榄油的摄入量呈负相关(p < 0.001)。相比之下,在男性和女性中,TFA 摄入量的四分位增加与肉类、香肠和糕点产品的摄入量增加呈正相关(p < 0.001)。
TFA 摄入与 2 型糖尿病风险增加无关。较高的 TFA 摄入与两性中更不健康的生活方式和饮食习惯有关。