Grosset Donald
Southern General Hospital, 1345 Govan Road, Glasgow, G51 4TF, UK.
IDrugs. 2010 Feb;13(2):82-4.
The XVIII World Federation of Neurology (WFN) World Congress on Parkinson's Disease and Related Disorders, held in Miami, FL, USA, included topics covering new therapeutic developments in this field. This conference report highlights selected presentations on the pathophysiology and treatment of these diseases, including the design of neuroprotective compounds, protein inhibition in the absence of catechol-O-methyltransferase (COMT), evaluating the striatal distribution of COMT, clinical results for PYM-50028 (Phytopharm plc) and ProSavin, and research into the use of stem cell treatments for Parkinson's disease.
第十八届世界神经病学联合会(WFN)帕金森病及相关疾病世界大会在美国佛罗里达州迈阿密举行,会议主题涵盖了该领域的新治疗进展。本会议报告重点介绍了关于这些疾病的病理生理学和治疗的精选演讲,包括神经保护化合物的设计、在缺乏儿茶酚-O-甲基转移酶(COMT)情况下的蛋白质抑制、评估COMT的纹状体分布、PYM-50028(Phytopharm plc)和ProSavin的临床结果,以及帕金森病干细胞治疗的研究。