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内镜下胆总管取石术围手术期极晚期药物洗脱支架血栓形成

Very late drug-eluting stent thrombosis in the perioperative period of endoscopic choledocholithotomy.

作者信息

Nie Ruqiong, Luo Niansang, Wang Jingfeng

机构信息

Department of Cardiology, Memorial Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.

出版信息

Acta Cardiol. 2009 Dec;64(6):831-3. doi: 10.2143/AC.64.6.2044754.

Abstract

Very late stent thrombosis is an uncommon but life-threatening complication after drug-eluting stent implantation in patients with coronary artery disease. Discontinuation of antiplatelet therapy is reported to be the most powerful predictor of stent thrombosis. This article reports on a case of very late stent thrombosis 54 months after implantation of a drug-eluting stent, in a patient who discontinued dual antiplatelet therapy only 11 days before endoscopic choledocholithotomy, and argues in favour of continuing aspirin therapy perioperatively in surgical patients with low bleeding risk, even if dual antiplatelet therapy has been followed more than 12 months after stent implantation.

摘要

极晚期支架血栓形成是冠心病患者药物洗脱支架植入术后一种罕见但危及生命的并发症。据报道,停用抗血小板治疗是支架血栓形成最有力的预测因素。本文报道了1例药物洗脱支架植入54个月后发生极晚期支架血栓形成的病例,该患者在内镜下胆总管取石术前仅11天停用双联抗血小板治疗,并主张对于出血风险低的外科手术患者,即使在支架植入后双联抗血小板治疗已超过12个月,围手术期也应继续使用阿司匹林治疗。

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