Yi Xian-Hua, Han Ya-Ling, Li Yi, Wang Shou-Li, Jing Quan-Min, Ma Ying-Yan, Wang Xiao-Zeng, Luan Bo, Wang Geng
Department of Cardiology, Cardiovascular Institute, General Hospital of Shenyang Command, Shenyang 110016, China.
Zhonghua Xin Xue Guan Bing Za Zhi. 2009 Sep;37(9):773-6.
To evaluate the long-term outcomes of successful or failed revascularization in patients with chronic total occlusions (CTO).
The clinical data of 1332 consecutive patients underwent percutaneous coronary intervention (PCI) for CTO between June 1993 and December 2006 in our hospital were analyzed. These patients were divided into two groups according to the procedural success (n = 1202) or failure (n = 130).
Overall success rate of procedure was 90.2% (1202/1332). The patients in CTO success group experienced a superior 10-year survival rate (76.9% vs. 64.6%, log rank P = 0.012) and a significantly higher no major adverse cardiovascular event (MACE) survival rate (41.8% vs. 27.6%, log rank P < 0.001) compared to the patients in CTO failure group. During the long-term follow-up, the proportion of patients who accepted coronary artery bypass grafting (CABG) was significantly lower in CTO success group than that in the CTO failure group (4.3% vs. 14.6%, P < 0.001).
Successful PCI procedure leads to increased long-term survival and MACE-free survival and the reduced need for CABG for patients with CTO lesions.
评估慢性完全闭塞（CTO）患者血管重建成功或失败的长期预后。
分析我院1993年6月至2006年12月期间连续1332例行CTO经皮冠状动脉介入治疗（PCI）患者的临床资料。这些患者根据手术成功（n = 1202）或失败（n = 130）分为两组。
手术总体成功率为90.2%（1202/1332）。与CTO失败组患者相比，CTO成功组患者的10年生存率更高（76.9%对64.6%，对数秩检验P = 0.012），无重大不良心血管事件（MACE）生存率显著更高（41.8%对27.6%，对数秩检验P < 0.001）。在长期随访期间，CTO成功组接受冠状动脉旁路移植术（CABG）的患者比例显著低于CTO失败组（4.3%对14.6%，P < 0.001）。
成功的PCI手术可提高CTO病变患者的长期生存率和无MACE生存率，并减少CABG的需求。
