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[一种新开发的自动体外除颤器在猪室性心动过速/心室颤动模型中的除颤效果]

[Defibrillation efficacy of a newly developed automated external defibrillator in a swine ventricular tachycardia/fibrillation model].

作者信息

Hui Jie, Gu Yun-Fei, Wu Xiao-Mei, Zhu Zong-Cheng, Song Jian-Ping, Yang Xiang-Jun, Liu Zhi-Hua, Jiang Ting-Bo, Fagn Zu-Xiang, Jiang Wen-Ping

机构信息

Department of Cardiology, First Hospital Affiliated to Suzhou University, Suzhou 215006, China.

出版信息

Zhonghua Xin Xue Guan Bing Za Zhi. 2009 Sep;37(9):845-8.

Abstract

OBJECTIVE

The aim of this study was to evaluate the recognition and defibrillation efficiency of a newly developed automated external defibrillator (AED).

METHOD

Ventricular tachycardia (VT)/ventricular fibrillation (VF) was induced by alternating current (50 Hz) through an electrode placed on apex of right ventricle in 23 anesthetized swine and recorded, recognized and defibrillated by a newly developed AED.

RESULTS

A total of 96 VF was induced and 145 defibrillations were recorded. We analyzed available 167 electrocardiosignal with a total length of 103,740 seconds. The accuracy, sensitivity and the specificity of the AED on VT/VF recognition are 99.5%, 98.2% and 99.6%, respectively. The success rate of defibrillation was 33.4% which increased in proportion to defibrillation energy. The defibrillation threshold of energy is 29.10-116.91 (78.75 +/- 35.64) J, the defibrillation threshold of electric quantity is (0.11 +/- 0.04) C and the defibrillation threshold of voltage is (1216.67 +/- 260.87) V.

CONCLUSIONS

This newly developed AED has high sensitivity and the specificity on recognizing VT/VF. The lower success rate of defibrillation of this AED is associated with the low defibrillation energy during defibrillation which needs to be improved on further development.

摘要

目的

本研究旨在评估一种新开发的自动体外除颤器(AED)的识别和除颤效率。

方法

通过放置在23只麻醉猪右心室心尖的电极,利用交流电(50Hz)诱发室性心动过速(VT)/室颤(VF),并由新开发的AED进行记录、识别和除颤。

结果

共诱发96次室颤,记录到145次除颤。我们分析了167份可用的心电图信号,总时长为103740秒。AED对VT/VF识别的准确率、灵敏度和特异性分别为99.5%、98.2%和99.6%。除颤成功率为33.4%,且与除颤能量成正比增加。能量除颤阈值为29.10 - 116.91(78.75±35.64)J,电量除颤阈值为(0.11±0.04)C,电压除颤阈值为(1216.67±260.87)V。

结论

这种新开发的AED在识别VT/VF方面具有高灵敏度和特异性。该AED较低的除颤成功率与除颤过程中较低的除颤能量有关,在进一步开发中需要改进。

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