Hui Jie, Gu Yun-Fei, Wu Xiao-Mei, Zhu Zong-Cheng, Song Jian-Ping, Yang Xiang-Jun, Liu Zhi-Hua, Jiang Ting-Bo, Fagn Zu-Xiang, Jiang Wen-Ping
Department of Cardiology, First Hospital Affiliated to Suzhou University, Suzhou 215006, China.
Zhonghua Xin Xue Guan Bing Za Zhi. 2009 Sep;37(9):845-8.
The aim of this study was to evaluate the recognition and defibrillation efficiency of a newly developed automated external defibrillator (AED).
Ventricular tachycardia (VT)/ventricular fibrillation (VF) was induced by alternating current (50 Hz) through an electrode placed on apex of right ventricle in 23 anesthetized swine and recorded, recognized and defibrillated by a newly developed AED.
A total of 96 VF was induced and 145 defibrillations were recorded. We analyzed available 167 electrocardiosignal with a total length of 103,740 seconds. The accuracy, sensitivity and the specificity of the AED on VT/VF recognition are 99.5%, 98.2% and 99.6%, respectively. The success rate of defibrillation was 33.4% which increased in proportion to defibrillation energy. The defibrillation threshold of energy is 29.10-116.91 (78.75 +/- 35.64) J, the defibrillation threshold of electric quantity is (0.11 +/- 0.04) C and the defibrillation threshold of voltage is (1216.67 +/- 260.87) V.
This newly developed AED has high sensitivity and the specificity on recognizing VT/VF. The lower success rate of defibrillation of this AED is associated with the low defibrillation energy during defibrillation which needs to be improved on further development.
本研究旨在评估一种新开发的自动体外除颤器（AED）的识别和除颤效率。
通过放置在23只麻醉猪右心室心尖的电极，利用交流电（50Hz）诱发室性心动过速（VT）/室颤（VF），并由新开发的AED进行记录、识别和除颤。
共诱发96次室颤，记录到145次除颤。我们分析了167份可用的心电图信号，总时长为103740秒。AED对VT/VF识别的准确率、灵敏度和特异性分别为99.5%、98.2%和99.6%。除颤成功率为33.4%，且与除颤能量成正比增加。能量除颤阈值为29.10 - 116.91（78.75±35.64）J，电量除颤阈值为（0.11±0.04）C，电压除颤阈值为（1216.67±260.87）V。
这种新开发的AED在识别VT/VF方面具有高灵敏度和特异性。该AED较低的除颤成功率与除颤过程中较低的除颤能量有关，在进一步开发中需要改进。
