Department of Biological and Medical Psychology, Division of Cognitive Neuroscience, University of Bergen, Norway.
Int J Neurosci. 2010 Jan;120(1):51-9. doi: 10.3109/00207450903275129.
Dyslexia is a condition characterized by difficulty of reading given adequate intelligence and educational opportunities, primarily associated with a phonological processing deficit. In this study we show that dyslexic children also show a deficit in working memory compared to a control group, measured with fMRI. A working memory n-back task with three load levels was used. Behavioral data showed that the dyslexics had poorer performance compared to the controls. fMRI data showed that the dyslexics had reduced activation in the prefrontal and parietal cortices and the cerebellum compared with the controls. These results imply a working memory deficit in dyslexia.
阅读障碍是一种以适当的智力和教育机会为特征的阅读困难，主要与语音处理缺陷有关。在这项研究中，我们使用 fMRI 显示阅读障碍儿童的工作记忆也存在缺陷，与对照组相比。使用了三个负载水平的工作记忆 n-back 任务。行为数据表明，阅读障碍者的表现比对照组差。fMRI 数据显示，与对照组相比，阅读障碍者的前额叶和顶叶皮层以及小脑的激活减少。这些结果表明阅读障碍存在工作记忆缺陷。
