• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Interaction of ligands with acetylcholinesterase. Use of temperature-jump relaxation kinetics in the binding of specific fluorescent ligands.

作者信息

Rosenberry T L, Neumann E

出版信息

Biochemistry. 1977 Aug 23;16(17):3870-8. doi: 10.1021/bi00636a024.

DOI:10.1021/bi00636a024
PMID:20130
Abstract
摘要

相似文献

1
Interaction of ligands with acetylcholinesterase. Use of temperature-jump relaxation kinetics in the binding of specific fluorescent ligands.
Biochemistry. 1977 Aug 23;16(17):3870-8. doi: 10.1021/bi00636a024.
2
Effective charge on acetylcholinesterase active sites determined from the ionic strength dependence of association rate constants with cationic ligands.根据与阳离子配体缔合速率常数的离子强度依赖性确定的乙酰胆碱酯酶活性位点上的有效电荷。
Biochemistry. 1980 Aug 5;19(16):3705-11. doi: 10.1021/bi00557a011.
3
Ligand binding properties of acetylcholinesterase determined with fluorescent probes.用荧光探针测定乙酰胆碱酯酶的配体结合特性。
Biochemistry. 1974 May 21;13(11):2299-307. doi: 10.1021/bi00708a010.
4
Equilibrium and kinetic studies of the interaction of site-specific ligands with acetylcholinesterase from Electrophorus electricus.电鳐乙酰胆碱酯酶位点特异性配体相互作用的平衡和动力学研究
Can J Biochem. 1978 Dec;56(12):1133-40. doi: 10.1139/o78-178.
5
Effects of quaternary ligands on the inhibition of acetylcholinesterase by arsenite.季铵配体对亚砷酸盐抑制乙酰胆碱酯酶的影响。
Biochemistry. 1977 Jun 14;16(12):2701-8. doi: 10.1021/bi00631a018.
6
Interactions of calcium with purified and intact cell acetylcholinesterase of Electrophorus electricus.钙与电鳗纯化及完整细胞乙酰胆碱酯酶的相互作用。
Biochem Pharmacol. 1974 Dec 15;23(24):3459-65. doi: 10.1016/0006-2952(74)90349-9.
7
[Inhibition of acetylcholinesterase using fluorescence-labeled inhibitors].[使用荧光标记抑制剂抑制乙酰胆碱酯酶]
Hoppe Seylers Z Physiol Chem. 1984 Dec;365(12):1475-87.
8
The effects of calcium and lanthanum on the interaction of decamethonium with soluble acetylcholinesterase from Electrophorus electricus.
J Neurochem. 1976 Jul;27(1):329-31. doi: 10.1111/j.1471-4159.1976.tb01594.x.
9
The effects of solubilization procedures on the release and molecular state of acetylcholinesterase from electric organ tissue.
J Neurochem. 1974 Dec;23(6):1177-87. doi: 10.1111/j.1471-4159.1974.tb12215.x.
10
Affinity chromatography of acetylcholinesterase from Electrophorus electricus electroplax. Investigations on 9-aminoalkylacridine affinity ligands.
J Chromatogr. 1983 Mar 4;257(2):275-84. doi: 10.1016/s0021-9673(01)88183-8.

引用本文的文献

1
Acetylcholinesterase: from 3D structure to function.乙酰胆碱酯酶：从 3D 结构到功能。
Chem Biol Interact. 2010 Sep 6;187(1-3):10-22. doi: 10.1016/j.cbi.2010.01.042. Epub 2010 Feb 4.
2
Novel anti-Alzheimer's dimer Bis(7)-cognitin: cellular and molecular mechanisms of neuroprotection through multiple targets.新型抗阿尔茨海默病二聚体双（7）-认知素：通过多个靶点实现神经保护的细胞和分子机制
Neurotherapeutics. 2009 Jan;6(1):187-201. doi: 10.1016/j.nurt.2008.10.040.
3
A modular treatment of molecular traffic through the active site of cholinesterase.
通过胆碱酯酶活性部位的分子流的模块化处理。
Biophys J. 1999 Nov;77(5):2430-50. doi: 10.1016/S0006-3495(99)77080-3.
4
Acetylcholinesterase: evidence that sodium ion binding at the anionic site causes inhibition of the second-order hydrolysis of acetylcholine and a decrease of its pKa as well as of deacetylation.乙酰胆碱酯酶：有证据表明，钠离子结合于阴离子位点会抑制乙酰胆碱的二级水解，并降低其pKa以及脱乙酰作用。
Biochem J. 1981 Jul 1;197(1):163-70. doi: 10.1042/bj1970163.
5
Quinacrine (mepacrine) action at frog end-plate.喹吖因（米帕林）对蛙终板的作用。
J Physiol. 1980 Sep;306:261-81. doi: 10.1113/jphysiol.1980.sp013396.
6
A covalently bound photoisomerizable agonist: comparison with reversibly bound agonists at Electrophorus electroplaques.一种共价结合的光异构化激动剂：与电鳐电板上可逆结合的激动剂的比较。
J Gen Physiol. 1980 Feb;75(2):207-32. doi: 10.1085/jgp.75.2.207.
7
NBD-5-acylcholine: fluorescent analog of acetylcholine and agonist at the neuromuscular junction.NBD - 5 - 酰基胆碱：乙酰胆碱的荧光类似物，也是神经肌肉接头处的激动剂。
Proc Natl Acad Sci U S A. 1979 Mar;76(3):1064-8. doi: 10.1073/pnas.76.3.1064.
8
Nerve excitability: transition from descriptive phenomenology to chemical analysis of mechanisms.神经兴奋性：从描述性现象学到机制的化学分析的转变。
Klin Wochenschr. 1977 Aug 1;55(15):715-23. doi: 10.1007/BF01476958.