手性噁唑硼烷阳离子催化的[4 + 2]环加成反应。反应速率以及非对映选择性、区域选择性和对映选择性取决于两个键是否同时形成。
[4 + 2] Cycloaddition reactions catalyzed by a chiral oxazaborolidinium cation. Reaction rates and diastereo-, regio-, and enantioselectivity depend on whether both bonds are formed simultaneously.
机构信息
Department of Chemistry and Chemical Biology, Harvard University,12 Oxford Street, Cambridge, Massachusetts 02138, USA.
出版信息
Org Lett. 2010 Mar 5;12(5):1024-7. doi: 10.1021/ol100032u.
PMID:20131879
Abstract
The reaction rates and products in enantioselective Diels-Alder reactions with a range of dienophiles correlate with the expected degree of concertedness of bond formation in the transition state.
摘要
在手性 Diels-Alder 反应中，与一系列亲双烯体的反应速率和产物与过渡态中键形成的协同程度相符。
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