Papanicolaou G A, Medeiros A A
Division of Infectious Diseases, Miriam Hospital, Providence, RI 02906.
Diagn Microbiol Infect Dis. 1991 Jan-Feb;14(1):85-7. doi: 10.1016/0732-8893(91)90094-v.
Ceftibuten, like cefotaxime, was observed to be a weak inducer of the class-I beta-lactamases of Enterobacter cloacae, Serratia marcescens, and Enterobacter aerogenes. In contrast, cefoxitin and imipenem induced these enzymes strongly at subinhibitory concentrations.
头孢布烯,与头孢噻肟一样,被观察到是阴沟肠杆菌、粘质沙雷氏菌和气生肠杆菌I类β-内酰胺酶的弱诱导剂。相比之下,头孢西丁和亚胺培南在亚抑菌浓度下能强烈诱导这些酶。