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[自膨式金属支架治疗恶性输尿管狭窄]

[Self-expanding metallic stents in malignant ureteral stenosis].

作者信息

Lugmayr H, Pauer W

机构信息

Abteilung Radiologie I, Krankenhaus der Barmherzigen Schwestern vom Heiligen Kreuz, Wels.

出版信息

Dtsch Med Wochenschr. 1991 Apr 12;116(15):573-6. doi: 10.1055/s-2008-1063651.

Abstract

Self-expanding metallic stents were inserted into the ureters of two female patients (29 and 46 years old) with malignant ureteric stenosis, in the first patient caused by metastases of a malignant melanoma, in the second by retroperitoneal lymph-node metastases from a colon carcinoma. In the first patient the stent was introduced antegrade into the left ureter via a nephrostomy after balloon dilatation of the stenotic segment. She was subsequently without symptoms, but six weeks later the ureter got kinked just above the bladder due to continued tumour growth against the stent. After insertion of a silicon splint she had no further symptoms referrable to the kidneys until she died two months later. In the other patient in whom both ureters were obstructed they could not be catheterized percutaneously. Stents were, therefore, introduced transurethrally after previous balloon dilatation of the stenoses. Obstruction occurred in the right ureter three days after the procedure due to mucosal oedema, but it was controlled by anti-inflammatory drugs. Hydronephrosis developed again six months later, caused by circumscribed incrustations in parts of the the stent not covered by mucosa. Silicon splints were placed bilaterally and the patient has so far been free of symptoms for two months.

摘要

自膨式金属支架被置入两名患有恶性输尿管狭窄的女性患者(分别为29岁和46岁)的输尿管中。第一位患者的恶性输尿管狭窄由恶性黑色素瘤转移所致,第二位患者的狭窄则由结肠癌的腹膜后淋巴结转移引起。在第一位患者中,经对狭窄段进行球囊扩张后,通过肾造瘘术将支架顺行置入左输尿管。随后她无症状,但六周后,由于肿瘤持续生长压迫支架,输尿管在膀胱上方发生扭结。插入硅胶夹板后,直到两个月后她去世,她都没有出现与肾脏相关的进一步症状。在另一位双侧输尿管均被阻塞的患者中,无法经皮进行输尿管插管。因此,在对狭窄部位进行球囊扩张后,经尿道置入支架。术后三天,右侧输尿管因黏膜水肿出现梗阻,但通过抗炎药物得以控制。六个月后,由于支架未被黏膜覆盖部分出现局限性结痂,再次发生肾积水。双侧放置了硅胶夹板,到目前为止,该患者已两个月无症状。

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