LGP2: positive about viral sensing.
作者信息
Moresco Eva Marie Y, Beutler Bruce
机构信息
Department of Genetics, The Scripps Research Institute, La Jolla, CA 92037, USA.
出版信息
Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1261-2. doi: 10.1073/pnas.0914011107.
Abstract
摘要
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本文引用的文献
1
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Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1512-7. doi: 10.1073/pnas.0912986107. Epub 2010 Jan 8.
2
RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway.RNA聚合酶III可检测胞质DNA，并通过RIG-I途径诱导I型干扰素产生。
Cell. 2009 Aug 7;138(3):576-91. doi: 10.1016/j.cell.2009.06.015. Epub 2009 Jul 23.
3
RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate.通过诱导RNA聚合酶III转录的RNA中间体，RIG-I依赖性地感知聚（dA:dT）。
Nat Immunol. 2009 Oct;10(10):1065-72. doi: 10.1038/ni.1779. Epub 2009 Jul 16.
4
Solution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptors.胞质RNA传感器MDA5和LGP2 C末端结构域的溶液结构：RIG-I样受体中RNA识别环的鉴定
J Biol Chem. 2009 Jun 26;284(26):17465-74. doi: 10.1074/jbc.M109.007179. Epub 2009 Apr 20.
5
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J Biol Chem. 2009 May 15;284(20):13881-13891. doi: 10.1074/jbc.M900818200. Epub 2009 Mar 11.
6
Regulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2.酶活性缺失的抗病毒RNA解旋酶蛋白MDA5、RIG-I和LGP2对信号转导的调控
J Biol Chem. 2009 Apr 10;284(15):9700-12. doi: 10.1074/jbc.M807365200. Epub 2009 Feb 11.
7
The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA.视黄酸诱导基因I（RIG-I）家族ATP酶LGP2的调节结构域可识别双链RNA。
Nucleic Acids Res. 2009 Apr;37(6):2014-25. doi: 10.1093/nar/gkp059. Epub 2009 Feb 10.
8
Structure and function of LGP2, a DEX(D/H) helicase that regulates the innate immunity response.LGP2的结构与功能，一种调节先天免疫反应的DEX（D/H）解旋酶
J Biol Chem. 2008 Jun 6;283(23):15825-33. doi: 10.1074/jbc.M800542200. Epub 2008 Apr 14.
9
Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses.维甲酸诱导基因I（RIG-I）解旋酶的非自身RNA传感机制与抗病毒免疫反应的激活
Mol Cell. 2008 Feb 29;29(4):428-40. doi: 10.1016/j.molcel.2007.11.028. Epub 2008 Jan 31.
10
Loss of DExD/H box RNA helicase LGP2 manifests disparate antiviral responses.DExD/H盒RNA解旋酶LGP2的缺失表现出不同的抗病毒反应。
J Immunol. 2007 May 15;178(10):6444-55. doi: 10.4049/jimmunol.178.10.6444.
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