University of Texas School of Public Health, Houston, TX, USA.
Am J Trop Med Hyg. 2010 Feb;82(2):301-5. doi: 10.4269/ajtmh.2010.09-0538.
This study evaluated occurrence of travel and travelers' diarrhea in patients with irritable bowel syndrome (IBS). A survey was mailed to 591 patients of a clinical practice who had IBS. Based on survey responses, patients were categorized as having IBS, post-infectious IBS (PI-IBS), unclassified functional bowel disorder (UFBD), or post-infectious UFBD (PI-UFBD). Of 201 persons who returned questionnaires meeting inclusion criteria, 57.7%, 11.4%, 24.9%, and 6.0% had IBS, UFBD, PI-IBS, and PI-UFBD, respectively. Travel during six months before illness onset was more common in patients with PI-IBS or PI-UFBD than in persons with idiopathic IBS or UFBD (P = 0.006). Survey results demonstrated that 16.1% of post-infectious bowel disorder cases and 7.5% of overall IBS cases in a general medical population developed chronic disease within six months of an international trip. Symptoms of established functional bowel disorder in each clinical category were shown to worsen after travel-related acute diarrhea.
本研究评估了旅行者腹泻在肠易激综合征（IBS）患者中的发生情况。对一家临床实践中的 591 名 IBS 患者进行了邮寄调查。根据调查结果，患者被分为 IBS、感染后肠易激综合征（PI-IBS）、未分类功能性肠病（UFBD）或感染后 UFBD（PI-UFBD）。在符合纳入标准的 201 名返回问卷的人中，分别有 57.7%、11.4%、24.9%和 6.0%的人患有 IBS、UFBD、PI-IBS 和 PI-UFBD。与特发性 IBS 或 UFBD 患者相比，PI-IBS 或 PI-UFBD 患者在发病前六个月内旅行的情况更为常见（P=0.006）。调查结果表明，在普通人群中，16.1%的感染后肠病病例和 7.5%的总体 IBS 病例在国际旅行后六个月内发展为慢性病。在每个临床类别中，已确立的功能性肠病症状在与旅行相关的急性腹泻后恶化。
