Program in Cellular Neuroscience, Neurodegeneration and Repair, Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut, USA.
Physiology (Bethesda). 2010 Feb;25(1):41-9. doi: 10.1152/physiol.00033.2009.
Glutamate receptors are major excitatory receptors in the brain. Recent findings have established auxiliary subunits of glutamate receptors as critical modulators of synaptic transmission, synaptic plasticity, and neurological disorder. The elucidation of the molecular rules governing glutamate receptors and subunits will improve our understanding of synapses and of neural-circuit regulation in the brain.
谷氨酸受体是大脑中的主要兴奋性受体。最近的研究发现，谷氨酸受体的辅助亚基是突触传递、突触可塑性和神经紊乱的关键调节因子。阐明调节谷氨酸受体和亚基的分子规则将有助于我们理解突触以及大脑中神经回路的调节。
