经皮血栓切除术对老年急性心肌梗死患者心肌微循环超声心动图测量指标的影响。

Effect of percutaneous thrombectomy on echocardiographic measures of myocardial microcirculation in elderly patients with acute myocardial infarction.

作者信息

Pan Wei, Liu Hong-Wei, Wang Lan-Feng, Li Zhu-Qin, Sun Xin-Yong

机构信息

Department of Cardiology, The First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang 150001, China.

出版信息

Coron Artery Dis. 2010 Mar;21(2):121-5. doi: 10.1097/MCA.0b013e32833729ca.

DOI:10.1097/MCA.0b013e32833729ca

PMID:20134319

Abstract

OBJECTIVES

To study the efficacy of percutaneous thrombectomy (PT) in improving myocardial microcirculation in elderly acute myocardial infarction (AMI) patients.

METHODS

A total of 104 patients (> or = 65 years) with AMI and coronary thrombus shown by angiography were randomly divided into a group of percutaneous coronary intervention (PCI) (n=52) and a group of PCI plus PT (n=52). At 24 h and 1 week after PCI, real-time myocardial contrast echocardiography was performed by contrast pulse sequencing technology. Contrast score index, contrast defect length/left ventricle length [CDL/LVL (%)], wall motion score index and wall motion abnormal length/LVL (%) were calculated.

RESULTS

At each time point, in patients treated with PCI plus PT, contrast score index, CDL/LVL (%), wall motion score index and wall motion abnormal length/LVL (%) were significantly lower than that in the PCI group.

CONCLUSION

Thrombectomy reduces the noreflow and the extent of microvascular obstruction, thus it was a feasible therapy in elderly patients with AMI.

摘要

目的

研究经皮血栓切除术（PT）改善老年急性心肌梗死（AMI）患者心肌微循环的疗效。

方法

共104例年龄≥65岁、经血管造影显示有冠状动脉血栓的AMI患者，随机分为经皮冠状动脉介入治疗（PCI）组（n = 52）和PCI联合PT组（n = 52）。PCI术后24小时和1周，采用对比脉冲序列技术进行实时心肌对比超声心动图检查。计算对比评分指数、对比缺损长度/左心室长度[CDL/LVL（%）]、壁运动评分指数和壁运动异常长度/LVL（%）。