Padmanabhan Hema
Endocrine Section, Department of Medicine, Veterans Affairs Medical Center, Salem, VA 24153, USA.
South Med J. 2010 Mar;103(3):272-5. doi: 10.1097/SMJ.0b013e3181ce0f30.
Primary hyperparathyroidism is commonly due to a single, sporadic parathyroid adenoma, and surgery is considered the treatment of choice based on guidelines established by the National Institutes of Health consensus panel. While there is no established medical therapy for this condition, pharmacotherapy with agents such as cinacalcet could be a preferred alternative in a subset of patients with persistent hypercalcemia after one or more surgical interventions.
原发性甲状旁腺功能亢进通常由单个散发性甲状旁腺腺瘤引起，根据美国国立卫生研究院共识小组制定的指南，手术被认为是首选治疗方法。虽然目前尚无针对这种疾病的确立的药物治疗方法，但对于在一次或多次手术干预后仍持续高钙血症的部分患者，使用西那卡塞等药物进行药物治疗可能是一种较好的选择。
