Chiarenza G A
Istituto di Neuropsichiatria Infantile, Università di Milano.
Ital J Neurol Sci. 1991 Feb;12(1):17-30. doi: 10.1007/BF02337610.
The methodological, developmental and clinical aspects of movement related brain macropotentials (MRBMs) are reviewed. The physiological differences between unskilled and skilled movements are described and the importance of interactive paradigms in studying movement organization from childhood to adulthood is emphasized. The developmental characteristics of the MRBMs in 119 normal males using a skilled motor perceptual task are presented together with a few clinical applications. This test has been performed by children with learning disabilities, boys with Down syndrome, subjects with chronic schizophrenia and patients with Parkinson syndrome. The results of the MRBMs are discussed for their relevance for our understanding of the cognitive processes and for their therapeutic implications.
本文综述了与运动相关的脑宏观电位（MRBMs）的方法学、发育和临床方面。描述了非熟练运动和熟练运动之间的生理差异，并强调了交互式范式在研究从儿童到成人运动组织中的重要性。介绍了119名正常男性在熟练运动感知任务中MRBMs的发育特征以及一些临床应用。学习障碍儿童、唐氏综合征男孩、慢性精神分裂症患者和帕金森综合征患者都进行了这项测试。讨论了MRBMs的结果与我们对认知过程的理解及其治疗意义的相关性。
