Le Gloan Laurianne, Guerin Patrice, Mercier Lise-Andrée, Abbey Sélim, Dore Annie, Marcotte François, Ibrahim Reda, Poirier Nancy C, Khairy Paul
Adult Congenital Heart Center, Montreal Heart Institute, University of Montreal, 5000 Belanger St E Montreal, H1T 1C8 QC, Canada.
Expert Rev Cardiovasc Ther. 2010 Feb;8(2):189-97. doi: 10.1586/erc.09.156.
As a major success story of an early surgical era, corrective surgery transformed the prognosis of patients born with tetralogy of Fallot. With lifelong care, healthy survival well into adulthood is now the norm, albeit somewhat blemished by long-term sequelae. Arrhythmias are an important source of morbidity and a leading cause of mortality. This succinct review provides a contemporary summary of the prevalence and types of arrhythmias encountered in tetralogy of Fallot, including conduction disorders, atrial and ventricular tachyarrhythmias, and sudden death. Current prognostic markers and existing diagnostic tools are discussed, and available therapeutic options are elaborated.
作为早期外科手术时代的一个重大成功案例,矫正手术改变了法洛四联症患儿的预后。通过终身护理,如今健康存活至成年已成为常态,尽管长期后遗症使其略有瑕疵。心律失常是发病的重要原因,也是死亡的主要原因。本简要综述对法洛四联症中出现的心律失常的患病率和类型进行了当代总结,包括传导障碍、房性和室性快速心律失常以及猝死。讨论了当前的预后标志物和现有的诊断工具,并详细阐述了可用的治疗选择。