Department of Internal Medicine, Jahrom University of Medical Sciences, Iran.
J Dtsch Dermatol Ges. 2010 May;8(5):348-52. doi: 10.1111/j.1610-0387.2010.07316.x. Epub 2010 Feb 3.
Near 20 % of people suffer from recurrent oral aphthous ulcers. These painful ulcers are found on the oral mucosa. We conducted this study to evaluate the effect of the camel thorn distillate on this condition.
93 patients with recurrent aphthous ulcers were selected and divided into two groups. One group was given a placebo (n = 44) and the other was given camel thorn distillate (n = 49). The diameter of the lesions and the severity of the pain were measured 3, 5, 7, 10 and 14 days after initiation of therapy. The lesion diameters and pain scores of the two groups were compared using the t-test.
Complete resolution time ranged from 3 to 7 days (mean = 4.02) in the group treated with camel thorn distillate, whereas in the control group, complete resolution time ranged from 7 to 14 days (mean = 8.9, p < 0.001).
The efficacy of camel thorn distillate is comparable to that of other drugs used to treat oral aphthous ulcers. Its therapeutic effect may be due to the flavanones (alhagitin and alhagidin) that are present in this plant.
近 20%的人患有复发性口腔溃疡。这些疼痛的溃疡出现在口腔黏膜上。我们进行这项研究是为了评估骆驼刺馏出物对此病症的疗效。
选择了 93 名复发性口腔溃疡患者，将其分为两组。一组给予安慰剂（n=44），另一组给予骆驼刺馏出物（n=49）。在治疗开始后第 3、5、7、10 和 14 天，测量了病变的直径和疼痛的严重程度。使用 t 检验比较两组的病变直径和疼痛评分。
用骆驼刺馏出物治疗的组中，完全缓解时间为 3 至 7 天（平均值=4.02），而在对照组中，完全缓解时间为 7 至 14 天（平均值=8.9，p<0.001）。
骆驼刺馏出物的疗效可与用于治疗口腔阿弗他溃疡的其他药物相媲美。其治疗效果可能归因于这种植物中存在的类黄酮（alhagitin 和 alhagidin）。
