Department of Pediatrics, University of Padova, Padova, ItalyMayer Children Hospital, Florence, Italy.
Acta Paediatr. 2010 May;99(5):758-762. doi: 10.1111/j.1651-2227.2010.01705.x. Epub 2010 Feb 5.
To analyse the methods used to manage and monitor sedoanalgesia at Italian paediatric intensive care units (ICUs).
Data were collected by administering a questionnaire that aimed to investigate whether ICUs adopted a validated protocol to manage sedoanalgesia.
The results revealed that a majority of the ICUs adopt a protocol for dealing with sedation and analgesia, but this protocol is implemented with difficulty or not at all in routine clinical practice. The most often used pharmacological combination, is midazolam and fentanyl. Several weaknesses remain in terms of the methods used to assess sedoanalgesia, which are generally not standardized, but rather based on recording the patient's physiological parameters.
Sedation and analgesia are priority issues in the management of critically ill children. None of the numerous drugs available is ideal and the protocols currently used in clinical practice involve the combined use of different drugs. There is currently no shared and validated approach as to which is the most effective and safest sedoanalgesic regimen in critically ill children.
分析意大利儿科重症监护病房（PICU）管理和监测镇静镇痛的方法。
通过问卷调查收集数据，旨在调查 PICU 是否采用了经过验证的镇静镇痛管理方案。
结果显示，大多数 PICU 采用了镇静和镇痛处理方案，但在常规临床实践中，该方案难以实施或根本不实施。最常使用的药物组合是咪达唑仑和芬太尼。在评估镇静镇痛的方法方面仍存在一些缺陷，这些方法通常没有标准化，而是基于记录患者的生理参数。
镇静和镇痛是危重症儿童管理的重点。目前尚无理想的药物，临床实践中使用的方案涉及联合使用不同的药物。目前，尚无针对危重症儿童最有效和最安全的镇静镇痛方案的共识和验证方法。
