Sasaki N
Department of Obstetrics and Gynecology, School of Medicine, Kitasato University, Kanagawa.
Nihon Sanka Fujinka Gakkai Zasshi. 1991 Feb;43(2):179-85.
Seventy-eight patients with condyloma acuminatum (51 with a lesion in the vulva, 11 in the uterine cervix, 1 in the vagina, 15 in multiple sites) have been treated by using three types of laser beam. The period to obtain epithelization after first treatment at the vulva, cervix and vagina was 4.4 +/- 1.8, 5.2 +/- 1.1 and 4.1 +/- 0.6 weeks (Mean +/- SD) respectively. The cure rates at the 10th week after first treatment and after first treatment during the follow-up periods between 10 weeks and 63 months were 78.2% (61/78) and 70.5% (55/78), respectively. The latter cure rates for each lesion were 70.3% in the vulva, 84.2% in the cervix and 72.7% in the vagina. In the recurrent group (62.5%), the incidence of partners with the disease was significantly higher (p less than 0.05) than that in the non-recurrent group (26.3%). No significant complication due to the therapy was found during or after treatment. This clinical study indicates that laser therapy is a useful method of treatment for condyloma acuminatum because of the short term healing with less complications and good cure rates.
78例尖锐湿疣患者（51例病变位于外阴，11例位于子宫颈，1例位于阴道，15例为多部位病变）接受了三种激光束治疗。在外阴、子宫颈和阴道首次治疗后达到上皮化的时间分别为4.4±1.8、5.2±1.1和4.1±0.6周（均值±标准差）。首次治疗后第10周以及随访期（10周～63个月）内首次治疗后的治愈率分别为78.2%（61/78）和70.5%（55/78）。各病变部位的后一治愈率分别为：外阴70.3%，子宫颈84.2%，阴道72.7%。在复发组（62.5%）中，性伴侣患该病的发生率显著高于非复发组（26.3%）（p<0.05）。治疗期间及治疗后未发现因该疗法导致的明显并发症。这项临床研究表明，激光治疗是一种治疗尖锐湿疣的有效方法，因为其愈合期短、并发症少且治愈率高。
