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[眼表肌电图信号分析研究]

[Study of ocular surface electromyography signal analysis].

作者信息

Zhu Bei, Qi Li-Ping

机构信息

The 4th Clinical Medical College of Peking University and Beijing Jishuitan Hospital, Beijing 100035, China.

出版信息

Zhonghua Yan Ke Za Zhi. 2009 Nov;45(11):977-81.

PMID:20137414
Abstract

OBJECTIVE

Test ocular surface electromyography signal waves and characteristic parameters to provide effective data for the diagnosis and treatment of ocular myopathy.

METHODS

Surface electromyography signals tests were performed in 140 normal volunteers and 30 patients with ophthalmoplegia. Surface electrodes were attached to medial canthi, lateral canthi and the middle of frontal bone. Then some alternate flashing red lamps were installed on perimeter to reduce the movement of eyeball. The computer hardware, software, and A/D adapter (12 Bit) were used. Sampling frequency could be selected within 40 kHz, frequency of amplifier was 2 kHz, and input short circuit noise was less than 3 microV.

RESULTS

For normal volunteers, the ocular surface electromyography signals were regular, and the electric waves were similar between different sex groups and age groups. While for patients with ophthalmoplegia, the wave amplitude of ocular surface electromyography signals were declined or disappeared in the dyskinesia direction. The wave amplitude was related with the degree of pathological process. The characteristic parameters of patients with ophthalmoplegia were higher than normal volunteers.

CONCLUSION

The figures of ocular surface electromyogram obtained from normal volunteers were obviously different with that from patients with ophthalmoplegia. This test can provide reliable quantized data for the diagnosis and treatment of ocular myopathy.

摘要

目的

检测眼表肌电图信号波形及特征参数,为眼肌病的诊断和治疗提供有效数据。

方法

对140名正常志愿者和30名眼肌麻痹患者进行表面肌电图信号检测。将表面电极附着于内眦、外眦和额骨中部。然后在视野计上安装一些交替闪烁的红灯以减少眼球运动。使用计算机硬件、软件和A/D适配器(12位)。采样频率可在40kHz内选择,放大器频率为2kHz,输入短路噪声小于3微伏。

结果

正常志愿者的眼表肌电图信号规则,不同性别组和年龄组之间的电波相似。而眼肌麻痹患者在运动障碍方向上眼表肌电图信号的波幅下降或消失。波幅与病理过程程度相关。眼肌麻痹患者的特征参数高于正常志愿者。

结论

正常志愿者获得的眼表肌电图图形与眼肌麻痹患者明显不同。该检测可为眼肌病的诊断和治疗提供可靠的量化数据。

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1
[Study of ocular surface electromyography signal analysis].[眼表肌电图信号分析研究]
Zhonghua Yan Ke Za Zhi. 2009 Nov;45(11):977-81.
2
Electromyographic study of the extrensic ocular muscles in a familial ocular myopathy.家族性眼肌病中外眼肌的肌电图研究
Electroencephalogr Clin Neurophysiol. 1969 Jul;27(1):99-100.
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[Ocular myopathy. III. Further observations on cases of ocular myopathy].
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Electromyography of the extraocular muscles in ophthalmoplegia.眼肌麻痹时眼外肌的肌电图检查
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[Electromyography in neurogenic and pseudoneurogenic disorders of ocular motility. IV. Characteristics of ocular myopathies--differential diagnosis].
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'Saccadic jitter' is a quantitative ocular sign in myasthenia gravis.“眼球震颤微颤”是重症肌无力的一种定量眼部体征。
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[A case of mitochondrial myopathy with progressive chronic ophthalmoplegia (author's transl)].一例伴进行性慢性眼肌麻痹的线粒体肌病(作者译)
Riv Patol Nerv Ment. 1977 Nov-Dec;98(6):333-46.
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