Wang Man, Lin Peng, Zhao Jin-kou, Li Yan, Zhang Qiao-li
Medical School of Jinan University, Guangzhou 510632, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2009 Nov;43(11):1004-8.
To understand the HIV epidemic and its correlation among the community-based drug users in Dongguan, Guangdong province.
In 2008, 13 drug users were identified as seeds in Dongguan. Respondent driven sampling was applied to recruit community-based drug users. A structured questionnaire was used for a face to face interview. Intravenous blood samples were collected for the measurement of HIV, HCV and syphilis antibodies. RDS analysis tool (RDSAT) was applied for adjusting the estimates and bivariate analysis.
A total of 303 drug users were recruited within 15 weeks and 300 blood samples were collected. After RDSAT adjustment, the prevalence rates of HIV, HCV and syphilis were 14.7% (95%CI: 6.1% - 25.4%), 63.2% (95%CI: 55.7% - 71.7%), and 4.7% (95%CI: 1.8% - 8.2%) respectively. The HIV prevalence rates among those who were HCV seropositive, migration, younger than 26 years at their first drug use, and ever shared needles or syringes were 22.9% (95%CI: 10.8% - 37.0%), 26.9% (95% CI: 11.4% - 44.9%), 19.9% (95%CI: 8.3% - 35.7%), and 29.1% (95%CI: 12.3% - 45.1%) respectively. The proportions of the drug users who were enrolled at methadone maintenance treatment (MMT) of local residency, migration were 20.9% (95%CI: 4.1% - 44.6%), 2.3% (95%CI: 0.0% - 7.0%) respectively.
The HIV epidemic among the community-based drug users in Dongguan is serious. Drug users who are HCV seropositive, migration, younger than 26 years at their first drug use, and ever shared needles or syringes are more likely to be HIV seropositive.
了解广东省东莞市社区吸毒人群中艾滋病病毒(HIV)的流行情况及其相关性。
2008年,在东莞识别出13名吸毒者作为种子。采用应答者驱动抽样方法招募社区吸毒人群。使用结构化问卷进行面对面访谈。采集静脉血样检测HIV、丙型肝炎病毒(HCV)和梅毒抗体。应用RDS分析工具(RDSAT)对估计值进行调整并进行双变量分析。
在15周内共招募了303名吸毒者,采集了300份血样。经RDSAT调整后,HIV、HCV和梅毒的患病率分别为14.7%(95%可信区间:6.1% - 25.4%)、63.2%(95%可信区间:55.7% - 71.7%)和4.7%(95%可信区间:1.8% - 8.2%)。HCV血清学阳性、有迁徙史、首次吸毒年龄小于26岁以及曾共用针头或注射器的吸毒者中,HIV患病率分别为22.9%(95%可信区间:10.8% - 37.0%)、26.9%(95%可信区间:11.4% - 44.9%)、19.9%(95%可信区间:8.3% - 35.7%)和29.1%(95%可信区间:12.3% - 45.1%)。参加当地社区美沙酮维持治疗(MMT)的吸毒者中,本地居民、有迁徙史者的比例分别为20.9%(95%可信区间:4.1% - 44.6%)、2.3%(95%可信区间:0.0% - 7.0%)。
东莞市社区吸毒人群中HIV流行情况严重。HCV血清学阳性、有迁徙史、首次吸毒年龄小于26岁以及曾共用针头或注射器的吸毒者更易感染HIV。