Department of Obstetrics and Gynecology, Meram Medicine Faculty, Selcuk University, Akyokus, 42080, Konya, Turkey.
Fertil Steril. 2010 May 1;93(7):2415-7. doi: 10.1016/j.fertnstert.2009.09.014. Epub 2010 Feb 4.
In this prospective study 294 patients diagnosed with ectopic pregnancy (EP) were treated with multiple-dose methotrexate (MTX) to determine the conversion rate to surgery. We concluded that multiple-dose MTX treatment had a low success rate, and the success rate was not related to initial b-hCG value; it was more related to the size of gestational mass before treatment.
在这项前瞻性研究中,294 例异位妊娠(EP)患者接受了多剂量甲氨蝶呤(MTX)治疗,以确定手术转化率。我们得出结论,多剂量 MTX 治疗成功率较低,且成功率与初始 b-hCG 值无关,而与治疗前妊娠囊大小更相关。