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利用固定可活动的载抗生素 spacer 来管理慢性肩部感染。

Management of chronic shoulder infections utilizing a fixed articulating antibiotic-loaded spacer.

机构信息

Department of Orthopedic Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

出版信息

J Shoulder Elbow Surg. 2010 Jul;19(5):739-48. doi: 10.1016/j.jse.2009.10.002. Epub 2010 Feb 4.

Abstract

BACKGROUND

Literature on management of chronic shoulder infections is limited. The purpose of this study was to examine the efficacy of a standardized protocol for the management of chronic shoulder infections, including periprosthetic infections, utilizing an articulating antibiotic-loaded spacer.

MATERIAL AND METHODS

Thirty patients with chronic shoulder infections (4 primary and 26 postoperative) were treated with aggressive debridement, implantation of an antibiotic-loaded articulating spacer, and systemic antibiotics. Twenty-seven patients (90%) were compromised hosts. Eighteen patients (group I) elected to keep the spacer but three patients later underwent reimplantation, thus fifteen patients (group IA) were using the spacer as a prosthesis at their latest follow-up of 2.4 years. Twelve patients (group II, follow-up of 2.3 years) underwent reimplantation of a prosthesis.

RESULTS

Eradication of infection was accomplished in all 30 patients. Group IA patients had a Disability of Arm Shoulder and Hand (DASH) score of 50, Simple Shoulder Test (SST) score of 5, forward flexion of 73 degrees, abduction of 71 degrees, and external rotation of 29 degrees. Group II patients had a DASH score of 58, SST score of 5, forward flexion of 78 degrees, abduction of 83 degrees, and external rotation of 19 degrees. The differences between these 2 groups were not significant.

DISCUSSION

Chronic shoulder infections can be successfully treated with a protocol of aggressive debridement, antibiotic-loaded articulating spacer, and systemic antibiotics. Prolonged implantation of an articulating spacer may be a viable option in select low-demand patients with comorbidities.

摘要

背景

慢性肩部感染的文献有限。本研究的目的是研究一种标准化方案治疗慢性肩部感染(包括假体周围感染)的疗效,该方案使用了带铰链的抗生素加载间隔物。

材料和方法

30 例慢性肩部感染患者(4 例原发性和 26 例术后)接受了积极清创术、植入带铰链的抗生素加载间隔物和全身抗生素治疗。27 例患者(90%)为宿主受损。18 例患者(组 I)选择保留间隔物,但 3 例患者后来进行了再植入,因此 15 例患者(组 IA)在 2.4 年的最新随访中使用间隔物作为假体。12 例患者(组 II,随访 2.3 年)进行了假体再植入。

结果

所有 30 例患者均成功消除感染。组 IA 患者的上肢功能障碍(DASH)评分为 50,简单肩部测试(SST)评分为 5,前屈 73 度,外展 71 度,外旋 29 度。组 II 患者的 DASH 评分为 58,SST 评分为 5,前屈 78 度,外展 83 度,外旋 19 度。这两组之间的差异没有统计学意义。

讨论

慢性肩部感染可以通过积极清创术、带铰链的抗生素加载间隔物和全身抗生素治疗方案成功治疗。在患有合并症的低需求患者中,长时间植入带铰链的间隔物可能是一种可行的选择。

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