[妊娠与2009年甲型H1N1流感大流行。麻醉与危重症医学的当前概念]

[Pregnancy and pandemic influenza A(H1N1) 2009. Current concepts for anaesthesia and critical care medicine].

作者信息

Dubar G, Launay O, Batteux F, Tsatsaris V, Goffinet F, Mignon A

机构信息

Département d'anesthésie-réanimation, groupe hospitalier Cochin, AP-HP, université Paris Descartes, 27 rue du Faubourg-Saint-Jacques, Paris cedex 14, France.

出版信息

Ann Fr Anesth Reanim. 2010 Feb;29(2):126-34. doi: 10.1016/j.annfar.2010.01.001.

DOI:10.1016/j.annfar.2010.01.001

PMID:20138461

Abstract

Pregnant women are particularly vulnerable to the pandemic influenza A(H1N1) 2009. Indeed, they are at high risk of developing a severe or fatal form of the disease. The physiological changes and the "immune deviation" from cellular to humoral immunity occurring during pregnancy are hypotheses to explain this vulnerability. Severe forms, mainly viral pneumonias, require an urgent prescription of an effective antiviral therapy. Preventive measures, mainly vaccination, are essential to avoid the appearance of these severe forms.

摘要

孕妇尤其容易感染2009年甲型H1N1大流行性流感。事实上，她们患重症或致命性该疾病的风险很高。孕期发生的生理变化以及从细胞免疫到体液免疫的“免疫偏移”是解释这种易感性的假说。重症形式，主要是病毒性肺炎，需要紧急开具有效的抗病毒治疗处方。预防措施，主要是接种疫苗，对于避免这些重症形式的出现至关重要。