Department of Medical Psychology and Psychiatry, Faculty of Medicine, Universidade Estadual de Campinas, Campinas, SP, Brazil.
Epilepsy Behav. 2010 Apr;17(4):483-8. doi: 10.1016/j.yebeh.2009.12.029.
Epilepsy has been associated with increased risk of suicide; however, few studies have examined the relationship between epilepsy and suicidal behavior. The aims of this study were to evaluate the frequency of suicidal behavior in people with epilepsy and to identify characteristics that are associated with suicidal ideation in epilepsy. Of 171 people with epilepsy identified in a previous survey, 139 were included. A structured interview was conducted, and a second psychiatric evaluation was scheduled for those who agreed. The frequencies of suicidal thoughts, plans, and attempts during lifetime were 36.7, 18.2, and 12.1%, respectively. The following conditions were strongly associated with suicidal thoughts: anxiety (OR=3.3, 95% CI=1.4-7.5, P=0.001), depression (OR=4.8, 95% CI=1.9-12.5, P=0.001), and two or more standardized psychiatric diagnoses (OR=21.6, 95% CI=4.4-105.9, P<0.0001). Although specific characteristics of epilepsy were found to be related to suicidal thoughts, psychiatric diseases also play an essential role.
癫痫与自杀风险增加有关；然而，很少有研究探讨癫痫与自杀行为之间的关系。本研究的目的是评估癫痫患者自杀行为的频率，并确定与癫痫患者自杀意念相关的特征。在之前的调查中确定了 171 名癫痫患者，其中 139 名被纳入本研究。对这些患者进行了结构化访谈，并安排那些同意的患者进行第二次精神病学评估。一生中出现自杀想法、计划和尝试的频率分别为 36.7%、18.2%和 12.1%。以下情况与自杀想法密切相关：焦虑（OR=3.3，95%CI=1.4-7.5，P=0.001）、抑郁（OR=4.8，95%CI=1.9-12.5，P=0.001）和两个或更多标准化精神诊断（OR=21.6，95%CI=4.4-105.9，P<0.0001）。尽管发现癫痫的特定特征与自杀想法有关，但精神疾病也起着至关重要的作用。
