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神经移位治疗臂丛神经根性撕脱伤:大鼠模型的实验研究

Nerve transfer for treatment of root avulsion of the brachial plexus: experimental studies in a rat model.

作者信息

Gu Y D, Ma M K

机构信息

Deparment of Hand Surgery, Hua Shan Hospital, Shanghai Medical University.

出版信息

J Reconstr Microsurg. 1991 Jan;7(1):15-22. doi: 10.1055/s-2007-1006759.

DOI:10.1055/s-2007-1006759
PMID:2013862
Abstract

In order to evaluate the effects of various nerve transfers, experimental rat models simulating root avulsions of the brachial plexus were created, using four different types of nerve transfers. Four groups of 160 rats were randomly divided, and phrenic nerves, double intercostal nerves, accessory nerves, and single intercostal nerves were transferred. Electrophysiologic and histologic examinations and functional evaluations were performed at different postoperative intervals. Phrenic nerve transfer was found to be superior to the other types most likely on the basis of superior neural regeneration. A single phrenectomy in the rat was found to have no apparent effect on pulmonary function.

摘要

为了评估各种神经移位的效果,利用四种不同类型的神经移位创建了模拟臂丛神经根撕脱伤的实验大鼠模型。将四组共160只大鼠随机分组,分别进行膈神经、双侧肋间神经、副神经和单侧肋间神经移位。在术后不同时间间隔进行电生理、组织学检查及功能评估。膈神经移位在神经再生方面可能最为优越,优于其他类型。研究发现,大鼠单次膈神经切除对肺功能无明显影响。

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