Loffeld S M L A, Loffeld R J L F
Department of Internal Medicine, Zaans Medisch Centrum, PO Box 210, 1500 EE, Zaandam, The Netherlands.
J Cancer Res Clin Oncol. 2010 Sep;136(9):1439-43. doi: 10.1007/s00432-010-0799-6. Epub 2010 Feb 6.
Colorectal cancer is one of the most common malignancies in the Western world. Screening and detection of its precursor lesion, the adenoma could prevent development of colorectal cancer. Many studies have been done to evaluate the prevalence of colorectal cancer in different countries. In daily practice, it was noticed that colorectal cancer was rarely seen in patients of Turkish decent.
To evaluate the prevalence of colorectal cancer and adenoma in patients living in the Zaanstreek region, the Netherlands, and correlate these findings with ethnicity.
All patients undergoing endoscopy of the colon and rectum during a period of 16 consecutive years in whom colorectal cancer and/or a polyp were diagnosed, were included in this study. All available histological data were retrieved in order to confirm the endoscopic diagnosis.
In the study period, 907 patients were diagnosed with colorectal cancer. Of these 13 (1.4%) were of Turkish descent (10 men and 3 women). The remaining 894 were authentic Dutch (473 men and 421 women). A total of 2,744 patients had one or more polyp(s) during endoscopy. There were 2,705 authentic Dutch (1,386 men, 1,319 women) and 39 Turkish patients (25 men, 14 women). There was no significant difference in gender in either of the groups.
Colorectal cancer and colonic adenoma are rare in patients of Turkish descent living in the Zaanstreek region, the Netherlands.
结直肠癌是西方世界最常见的恶性肿瘤之一。筛查和检测其前驱病变腺瘤可预防结直肠癌的发生。已经开展了许多研究来评估不同国家结直肠癌的患病率。在日常实践中，人们注意到土耳其裔患者中很少见到结直肠癌。
评估居住在荷兰赞斯特雷克地区的患者中结直肠癌和腺瘤的患病率，并将这些结果与种族进行关联。
本研究纳入了连续16年期间所有接受结肠和直肠内镜检查且被诊断为结直肠癌和/或息肉的患者。检索所有可用的组织学数据以确认内镜诊断。
在研究期间，907例患者被诊断为结直肠癌。其中13例（1.4%）为土耳其裔（10名男性和3名女性）。其余894例为正宗荷兰人（473名男性和421名女性）。共有2744例患者在内镜检查时有一个或多个息肉。其中有2705例正宗荷兰人（1386名男性，1319名女性）和39例土耳其患者（25名男性，14名女性）。两组在性别上均无显著差异。
居住在荷兰赞斯特雷克地区的土耳其裔患者中，结直肠癌和结肠腺瘤较为罕见。
