Dipartimento di Biologia Vegetale, Universita degli Studi di Roma 'Sapienza', Rome, Italy.
Nat Prod Res. 2010 Feb;24(3):286-93. doi: 10.1080/14786410903006353.
Hypericum perforatum is an important medicinal plant containing numerous biologically active compounds. The effect of chitosan elicitation on xanthone biosynthesis in calli and in cell suspension cultures of H. perforatum subsp. angustifolium was evaluated. Elicited cell cultures showed an increase in xanthone production and a simultaneous decrease in flavonoid production. Chitosan also induced the production of 1,7-dihydroxyxanthone (euxanthone) and cadensin G, which were not detected in either the calli nor the non-elicited cell cultures. 1,7-Dihydroxyxanthone was in part (21%) released in the culture medium.
贯叶金丝桃是一种重要的药用植物，含有许多具有生物活性的化合物。本文评价了壳聚糖对贯叶金丝桃亚种狭叶金丝桃愈伤组织和细胞悬浮培养物中黄烷酮生物合成的诱导作用。诱导后的细胞培养物中黄烷酮的产量增加，同时黄酮类化合物的产量减少。壳聚糖还诱导产生了 1,7-二羟基黄烷酮（大黄素）和卡登辛 G，在愈伤组织和未诱导的细胞培养物中均未检测到这两种物质。1,7-二羟基黄烷酮有部分（21%）释放到培养基中。
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