Morse Michael A, Whelan Michael
Duke University Medical Center, Durham, NC 27710, USA.
Curr Opin Mol Ther. 2010 Feb;12(1):11-3.
Results from recent clinical trials of the therapeutic vaccines sipuleucel-T (Dendreon Corp), PROSTVAC-VF-TRICOM (National Cancer Institute/BN ImmunoTherapeutics Inc) and BiovaxID (Biovest International Inc) are highlighted. These data support the further development of such vaccines, and provide guidance for the development of improved agents and protocols for the use of therapeutic vaccination to treat cancer.
近期针对治疗性疫苗sipuleucel-T(丹德昂公司)、PROSTVAC-VF-TRICOM(美国国立癌症研究所/BN免疫治疗公司)和BiovaxID(百维斯国际公司)的临床试验结果得到了重点介绍。这些数据支持此类疫苗的进一步研发,并为开发改良药物以及制定使用治疗性疫苗治疗癌症的方案提供了指导。