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Relationship of the reduced folate carrier gene polymorphism G80A to methotrexate plasma concentration, toxicity, and disease outcome in childhood acute lymphoblastic leukemia.

作者信息

Faganel Kotnik Barbara, Dolzan Vita, Grabnar Iztok, Jazbec Janez

出版信息

Leuk Lymphoma. 2010 Apr;51(4):724-6. doi: 10.3109/10428191003611402.

DOI:10.3109/10428191003611402
PMID:20141435
Abstract
摘要

相似文献

1
Relationship of the reduced folate carrier gene polymorphism G80A to methotrexate plasma concentration, toxicity, and disease outcome in childhood acute lymphoblastic leukemia.还原型叶酸载体基因多态性G80A与儿童急性淋巴细胞白血病中甲氨蝶呤血药浓度、毒性及疾病转归的关系。
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2
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The effect of RFC G80A polymorphism in Cretan children with acute lymphoblastic leukemia and its interaction with MTHFR C677T and A1298C polymorphisms.克里特岛急性淋巴细胞白血病患儿中 RFC G80A 多态性的影响及其与 MTHFR C677T 和 A1298C 多态性的相互作用。
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6
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The association of reduced folate carrier 80G>A polymorphism to outcome in childhood acute lymphoblastic leukemia interacts with chromosome 21 copy number.叶酸载体 80G>A 多态性与儿童急性淋巴细胞白血病的预后相关，且与 21 号染色体拷贝数相关。
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引用本文的文献

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The Role of Genetic Polymorphisms in High-Dose Methotrexate Toxicity and Response in Hematological Malignancies: A Systematic Review and Meta-Analysis.基因多态性在血液系统恶性肿瘤高剂量甲氨蝶呤毒性及反应中的作用：一项系统评价和荟萃分析
Front Pharmacol. 2021 Oct 21;12:757464. doi: 10.3389/fphar.2021.757464. eCollection 2021.
2
Association between Gene Polymorphism and High Dose Methotrexate Toxicity in Childhood Acute Lymphoblastic Leukaemia and Non Hodgkin Malignant Lymphoma: Introducing a Haplotype based Approach.儿童急性淋巴细胞白血病和非霍奇金恶性淋巴瘤中基因多态性与高剂量甲氨蝶呤毒性之间的关联：引入基于单倍型的方法。
Radiol Oncol. 2017 Sep 18;51(4):455-462. doi: 10.1515/raon-2017-0040. eCollection 2017 Dec.
3
Uptake carriers and oncology drug safety.
摄取载体和肿瘤药物安全。
Drug Metab Dispos. 2014 Apr;42(4):611-22. doi: 10.1124/dmd.113.055806. Epub 2013 Dec 30.
4
Association of genetic polymorphism in the folate metabolic pathway with methotrexate pharmacokinetics and toxicity in childhood acute lymphoblastic leukaemia and malignant lymphoma.叶酸代谢途径中遗传多态性与儿童急性淋巴细胞白血病和恶性淋巴瘤中甲氨蝶呤药代动力学和毒性的关系。
Eur J Clin Pharmacol. 2011 Oct;67(10):993-1006. doi: 10.1007/s00228-011-1046-z. Epub 2011 Apr 21.