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美国女性令人苦恼的性问题再探讨:考虑到抑郁后,其患病率。

Distressing sexual problems in United States women revisited: prevalence after accounting for depression.

机构信息

Department of Pharmacoepidemiology and Risk Management, Research Triangle Institute (RTI) Health Solutions, Waltham, Massachusetts 02451, USA.

出版信息

J Clin Psychiatry. 2009 Dec;70(12):1698-706. doi: 10.4088/JCP.09m05390gry.

Abstract

OBJECTIVE

With data from the population-based Prevalence of Female Sexual Problems Associated with Distress and Determinants of Treatment Seeking (PRESIDE) study, which has previously estimated the prevalence of sexual problems and sexually related personal distress in United States women, the prevalence of sexual disorders of desire, arousal, and orgasm was re-estimated, taking concurrent depression into consideration.

METHOD

Current depression was defined in 3 ways as (1) self-reported symptoms alone, (2) antidepressant medication use alone, or (3) symptoms and/or antidepressant use. The unadjusted population prevalence for each distressing sexual problem in the 31,581 respondents was calculated first irrespective of concurrent depression and then in women without concurrent depression, thus determining the size of the population with both conditions present.

RESULTS

The unadjusted population-based prevalence of desire disorder was 10.0% and was reduced to 6.3% for those without concurrent depression, leading to an estimate of 3.7% for those with both conditions present. The same pattern was observed for arousal and orgasm disorders, although overall prevalence estimates were lower.

CONCLUSIONS

Our findings indicate that about 40% of those with a sexual disorder of desire, arousal, or orgasm have concurrent depression, As this study was cross-sectional, causality versus comorbidity cannot be determined. However, our findings stress the importance of evaluating depression along with sexual problems in routine clinical practice and epidemiology research.

摘要

目的

利用基于人群的“与困扰相关的女性性问题的流行率及治疗寻求的决定因素(PRESIDE)研究”的数据,该研究先前估计了美国女性性问题和与性相关的个人困扰的流行率,本研究重新估计了性欲、唤起和性高潮障碍的流行率,并考虑了同时存在的抑郁。

方法

当前的抑郁以 3 种方式定义:(1)仅报告症状,(2)仅使用抗抑郁药,或(3)症状和/或使用抗抑郁药。在 31581 名应答者中,首先计算出每个困扰性问题的未调整人群流行率,无论是否同时存在抑郁,然后在没有同时存在抑郁的女性中计算,从而确定同时存在两种情况的人群规模。

结果

未调整的基于人群的性欲障碍流行率为 10.0%,而无同时存在抑郁的患者的流行率降低至 6.3%,这导致同时存在两种情况的患者的估计流行率为 3.7%。对于唤起和性高潮障碍,也观察到了相同的模式,尽管总体流行率估计较低。

结论

我们的发现表明,约 40%的性欲、唤起或性高潮障碍患者同时存在抑郁,由于本研究是横断面研究,因此无法确定因果关系与共病关系。然而,我们的发现强调了在常规临床实践和流行病学研究中评估抑郁与性问题的重要性。

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