Morvan Y, Rouvier J, Olié J-P, Lôo H, Krebs M-O
Laboratoire de Physiopathologie des Maladies Psychiatriques, Université Paris Descartes, Inserm, Centre Psychiatrie et Neurosciences, U894, Paris, France.
Encephale. 2009 Dec;35 Suppl 6:S202-8. doi: 10.1016/S0013-7006(09)73471-2.
The use of illicit drugs by students and the possible psychological repercussions in this population of young adults is an important public health issue. While some data in the literature suggest a relationship between cannabis and the occurrence of mental health disorders, and in particular psychotic illnesses, epidemiologic surveys have shown that cannabis is the most consumed illicit drug in France.
To carry out a quantitative and qualitative epidemiological investigation of substance use within a student population seen during their mandatory preventive health visit at the University medical facility.
Students were asked to take part in an investigation of their substance consumption and their individual experiences with cannabis in particular. Personality autoquestionnaires were performed and the psychotomimetic effects of cannabis were investigated with substance use within a student population seen during their mandatory preventive health visit at the University medical facility.
A total of 3,807 students took part in the survey with a response rate of approximately 50%. Preliminary results relating to a subsample of this study are presented here (n = 880, mean age 20 years, 65% women). 44% of the students consumed cannabis at least once in their life. The prevalence of regular consumption in students (at least once a week) was of 18%, 11% had periods of daily or close to daily consumptions, and 13% used cannabis in the last month. For each of the drugs cocaine, ecstasy (MDMA), and mushrooms (psilocybin) the prevalence of experimentation (at least once) was 5% for cocaine, 4% for ecstasy and mushrooms, and for LSD the rate was 1,5%. Other evaluated substances had a prevalence of consumption lower than 1%. For the first cannabis consumptions, a majority of students state to felt "pleasant" effects: relaxation (71%) and euphoria (53%). 13% state to have felt effects of anxiety or sadness. 25% admit having had difficulties of expression, 24% memory deficits, 35% trouble with coordination or balance and 39% difficulties of concentration. Approximately 16% had impressions of depersonalization and derealization. Lastly, some experienced "psychotic-like" effects such as visual (10%) and auditory (6%) hallucinations, as well as referential ideas (16%), mistrust or feelings of persecution (11%). 26% of the student sample had felt at least one of these last four "psychotic-like" effects.
The results are consistent with the idea that the impact of cannabis consumption is highly variable among different consumers. Implications for prevention strategies are discussed such as educational interventions based on recognition and motivation for change.
学生使用非法药物以及这一年轻人群体可能产生的心理影响是一个重要的公共卫生问题。虽然文献中的一些数据表明大麻与心理健康障碍尤其是精神病性疾病的发生之间存在关联,但流行病学调查显示大麻是法国消费最多的非法药物。
对在大学医疗机构进行强制性预防性健康检查的学生群体中的物质使用情况进行定量和定性的流行病学调查。
要求学生参与对其物质消费情况的调查,特别是他们使用大麻的个人经历。进行了人格自填问卷,并通过对在大学医疗机构进行强制性预防性健康检查的学生群体中的物质使用情况来研究大麻的拟精神病效应。
共有3807名学生参与了调查,回复率约为50%。这里展示了本研究一个子样本的初步结果(n = 880,平均年龄20岁,65%为女性)。44%的学生一生中至少使用过大麻一次。学生中经常使用大麻(至少每周一次)的患病率为18%,11%有每日或接近每日使用大麻的时期,13%在过去一个月内使用过大麻。对于可卡因、摇头丸(MDMA)和蘑菇(裸盖菇素)这三种毒品,尝试(至少一次)的患病率分别为:可卡因为5%,摇头丸和蘑菇为4%,而麦角酸二乙胺(LSD)的使用率为1.5%。其他评估的物质使用率低于1%。对于首次使用大麻的情况,大多数学生表示有“愉悦”的效果:放松(71%)和欣快感(53%)。13%的学生表示有焦虑或悲伤的感觉。25%的学生承认有表达困难,24%有记忆缺陷,35%有协调或平衡问题,39%有注意力不集中的问题。约16%的学生有去人格化和现实解体的感觉。最后,一些学生经历了“类精神病性”效应,如视觉幻觉(10%)和听觉幻觉(6%),以及牵连观念(16%)、不信任或受迫害感(11%)。26%的学生样本至少有过这四种“类精神病性”效应中的一种。
结果与大麻消费对不同消费者的影响差异很大这一观点一致。讨论了对预防策略的启示,如基于认知和改变动机的教育干预措施。