Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
Cell. 2010 Jan 22;140(2):180-2. doi: 10.1016/j.cell.2010.01.013.
Targeted molecular therapies for cancer treatment have shown promise, but also have limitations. In this issue, Heidorn et al. (2010) find that a class of targeted molecular therapies with clinical effectiveness against one melanoma subtype may have adverse clinical effects in another.
针对癌症治疗的靶向分子疗法显示出了前景,但也存在局限性。在本期杂志中,Heidorn 等人(2010)发现,一类针对一种黑色素瘤亚型具有临床疗效的靶向分子疗法,可能在另一种亚型中具有不良的临床效果。