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2007 年健康信息全国趋势调查(HINTS)中 HPV 疫苗可接受性的行为相关性。

Behavioral correlates of HPV vaccine acceptability in the 2007 Health Information National Trends Survey (HINTS).

机构信息

Cancer Prevention and Control Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.

出版信息

Cancer Epidemiol Biomarkers Prev. 2010 Feb;19(2):319-26. doi: 10.1158/1055-9965.EPI-09-0918.

Abstract

The development of a prophylactic vaccine to prevent infection with oncogenic subtypes of human papillomavirus (HPV) is an important step in reducing cervical cancer incidence and mortality. However, national data indicate that only 37% of 13- to 17-year-old females have initiated the vaccine series. Prior studies have examined demographic, medical history, and psychosocial variables associated with parental HPV vaccine acceptability, although few have investigated the behavioral correlates of vaccine acceptability. The primary purpose of the current study is to report on national acceptability of the HPV vaccine among U.S. adults with female children in the household and to investigate the health behavior correlates of vaccine acceptability. Data were drawn from the 2007 Health Information National Trends Survey (HINTS). The study sample comprised 1,383 adults who reported having a female child under the age of 18 in their household (52% female, 59% white; mean age = 40 years). More than half (58%) reported they would have a daughter get the HPV vaccine, 25% were not sure, and 18% would not have a daughter vaccinated. Behavioral factors significantly associated with lower acceptance of the HPV vaccine included lack of physical activity in the past month (P = 0.002), past year use of complementary or alternative therapies (P = 0.021), and no history of smoking (P = 0.005). These results suggest that behavioral health factors may be associated with vaccine acceptability and further our understanding of how behavioral patterns may contribute to the uptake of new cancer prevention strategies.

摘要

开发预防性疫苗以预防致癌人乳头瘤病毒(HPV)亚型感染是降低宫颈癌发病率和死亡率的重要步骤。然而,国家数据表明,只有 37%的 13 至 17 岁女性开始接种疫苗系列。先前的研究已经研究了与父母 HPV 疫苗可接受性相关的人口统计学、病史和心理社会变量,尽管很少有研究调查疫苗可接受性的行为相关性。本研究的主要目的是报告美国有女性子女的成年人对 HPV 疫苗的全国可接受性,并调查疫苗可接受性的健康行为相关性。数据来自 2007 年健康信息国家趋势调查(HINTS)。研究样本包括 1383 名报告家中有 18 岁以下女性子女的成年人(52%为女性,59%为白人;平均年龄为 40 岁)。超过一半(58%)的人表示他们会让女儿接种 HPV 疫苗,25%的人不确定,18%的人不会让女儿接种疫苗。与 HPV 疫苗接受度较低显著相关的行为因素包括过去一个月缺乏体育锻炼(P=0.002)、过去一年使用补充或替代疗法(P=0.021)以及没有吸烟史(P=0.005)。这些结果表明,行为健康因素可能与疫苗可接受性有关,并进一步了解行为模式如何有助于新的癌症预防策略的实施。

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