Mirowitz S A, Lee J K, Gutierrez E, Brown J J, Heiken J P, Eilenberg S S
Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110.
Radiology. 1991 May;179(2):371-6. doi: 10.1148/radiology.179.2.2014277.
Rapid acquisition spin-echo (RASE) magnetic resonance (MR) imaging allows for coverage of the entire liver with highly T1-weighted SE images during a single 23-second breath-holding period. The RASE sequence was implemented in conjunction with rapid intravenous injection of gadopentetate dimeglumine to enable performance of dynamic contrast material-enhanced MR imaging of the liver. Prospective evaluation of 24 patients with 62 liver lesions 1 cm or greater in diameter was performed. Images obtained with RASE were devoid of respiratory-related ghost artifacts or edge blurring. The dynamic contrast-enhanced RASE technique resulted in contrast-to-noise and contrast-to-artifact values and time efficiency measures significantly greater (P less than .05) than those obtained with use of conventional T1- and T2-weighted pulse sequences, indicating a higher likelihood for lesion detectability. Lesion conspicuity was maximal during or immediately following bolus administration of gadopentetate dimeglumine, with lesions often becoming obscured at delayed postcontrast imaging.
快速采集自旋回波（RASE）磁共振（MR）成像能够在单次23秒屏气期间，用高度T1加权的SE图像覆盖整个肝脏。RASE序列与快速静脉注射钆喷酸葡胺联合使用，以实现肝脏动态对比剂增强MR成像。对24例患有62个直径1厘米或更大肝脏病变的患者进行了前瞻性评估。用RASE获得的图像没有呼吸相关的鬼影伪影或边缘模糊。动态对比增强RASE技术产生的对比噪声比、对比伪影比和时间效率指标显著高于（P小于0.05）使用传统T1加权和T2加权脉冲序列获得的指标，表明病变可检测性更高。在静脉推注钆喷酸葡胺期间或之后立即，病变的清晰度最高，在延迟的对比后成像时病变常常变得模糊不清。
