Kopecky K K, Braunstein E M, Brandt K D, Filo R S, Leapman S B, Capello W N, Klatte E C
Department of Radiology, Indiana University Medical Center, Indianapolis.
Radiology. 1991 May;179(2):523-7. doi: 10.1148/radiology.179.2.2014304.
The sensitivity of magnetic resonance (MR) imaging in the detection of avascular necrosis (AVN) of the hip and natural history of the MR findings were determined prospectively in renal allograft recipients, a group at risk for development of the disease. One hundred four patients were studied up to 24 months after transplantation. In 25 hips in 14 patients, MR findings were consistent with AVN. Pain developed in seven hips in four patients; in each hip, the MR images showed abnormality before the onset of symptoms. Plain radiographs showed abnormality in all hips that became painful; however, the plain radiographs of 17 of 18 asymptomatic hips in which MR imaging showed evidence of AVN showed no abnormality over a mean follow-up period of 16 months. All MR lesions in the symptomatic hips were larger than those in the asymptomatic cohort. MR lesions in seven hips (in five asymptomatic patients) regressed in size; in six hips, the MR images returned to normal. The findings suggest that some patients with MR evidence of AVN of the hip have spontaneous improvement.
对肾移植受者(该疾病的高危人群)前瞻性地确定了磁共振(MR)成像检测髋关节缺血性坏死(AVN)的敏感性以及MR表现的自然病程。对104例患者进行了长达移植后24个月的研究。14例患者的25个髋关节中,MR表现符合AVN。4例患者的7个髋关节出现疼痛;每个髋关节在症状出现前MR图像均显示异常。所有出现疼痛的髋关节X线平片均显示异常;然而,18个无症状髋关节中17个的X线平片在平均16个月的随访期内未显示异常,而这些髋关节的MR成像显示有AVN证据。有症状髋关节的所有MR病变均大于无症状队列中的病变。7个髋关节(5例无症状患者)的MR病变大小缩小;6个髋关节的MR图像恢复正常。这些发现表明,一些有髋关节AVN的MR证据的患者有自发改善。