Department of Chemistry, National Taiwan University, Taipei 106, Taiwan.
Inorg Chem. 2010 Mar 15;49(6):3011-8. doi: 10.1021/ic9025188.
A series of designed palladium biscarbene complexes including saturated and unsaturated N-heterocyclic carbene (NHC) moieties have been prepared by the carbene transfer methods. All of these complexes have been characterized by (1)H and (13)C NMR spectroscopy as well as X-ray diffraction analysis. The reactivity of Pd-C((saturated NHC)) is distinct from that of Pd-C((unsaturated NHC)). The Pd-C((saturated NHC)) bonds are fairly stable toward reagents such as CF(3)COOH, AgBF(4) and I(2), whereas Pd-C((unsaturated NHC)) bonds are readily cleaved under the similar conditions. Notably, the catalytically activity of these palladium complexes on Suzuki-Miyaura coupling follows the order: (sat-NHC)(2)PdCl(2) > (sat-NHC)(unsat-NHC)PdCl(2 )> (unsat-NHC)(2)PdCl(2).
一系列设计的钯双卡宾配合物，包括饱和和不饱和的 N-杂环卡宾（NHC）部分，已经通过卡宾转移方法制备。所有这些配合物都通过（1）H 和（13）C NMR 光谱以及 X 射线衍射分析进行了表征。Pd-C（（饱和 NHC））的反应性与 Pd-C（（不饱和 NHC））的反应性明显不同。Pd-C（（饱和 NHC））键对 CF（3）COOH、AgBF（4）和 I（2）等试剂相当稳定，而 Pd-C（（不饱和 NHC））键在类似条件下容易断裂。值得注意的是，这些钯配合物在 Suzuki-Miyaura 偶联反应中的催化活性遵循以下顺序：（sat-NHC）（2）PdCl（2）>（sat-NHC）（unsat-NHC）PdCl（2）>（unsat-NHC）（2）PdCl（2）。
