Arnold and Mabel Beckman Laboratories of Chemical Synthesis, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.
J Am Chem Soc. 2011 Jun 8;133(22):8498-501. doi: 10.1021/ja203070r. Epub 2011 May 16.
The synthesis of a ruthenium complex containing an N-heterocylic carbene (NHC) and a mesoionic carbene (MIC) is described wherein addition of a Brønsted acid results in protonolysis of the Ru-MIC bond to generate an extremely active metathesis catalyst. Mechanistic studies implicated a rate-determining protonation step in the generation of the metathesis-active species. The activity of the NHC/MIC catalyst was found to exceed those of current commercial ruthenium catalysts.
本文描述了一种含有 N-杂环卡宾(NHC)和中氮茚卡宾(MIC)的钌配合物的合成方法,其中加入布朗斯台德酸会导致 Ru-MIC 键质子化,从而生成一种非常活跃的复分解催化剂。机理研究表明,在生成具有复分解活性的物种过程中,质子化是速率决定步骤。该 NHC/MIC 催化剂的活性超过了当前商业钌催化剂。