Ridout A E, Yoong W
University College London Medical School, London, UK.
J Obstet Gynaecol. 2010 Feb;30(2):111-4. doi: 10.3109/01443610903428922.
Overactive bladder syndrome is defined as a symptom syndrome which includes urinary urgency, with or without urge incontinence, usually accompanied by frequency (>8 micturitions/24 h) and nocturia. Conservative treatment usually comprises behavioural techniques, bladder retraining, pelvic floor re-education and pharmacotherapy but up to 30% of patients will remain refractory to treatment. Although second-line treatment options such as sacral nerve stimulation and intravesical botulinum A injections are valuable additions to the therapeutic arsenal, they are relatively invasive and can have serious side-effects. Inhibition of detrusor activity by peripheral neuromodulation of the posterior tibial nerve was first described in 1983, with recent authors further confirming a 60-80% positive response rate. This review was undertaken to examine published literature on percutaneous tibial nerve stimulation and to discuss outcome measures, maintenance therapy and prognostic factors of this technique.
膀胱过度活动症综合征被定义为一种症状综合征，包括尿急，伴有或不伴有急迫性尿失禁，通常伴有尿频（>8次排尿/24小时）和夜尿症。保守治疗通常包括行为技术、膀胱再训练、盆底再教育和药物治疗，但高达30%的患者对治疗仍无反应。尽管诸如骶神经刺激和膀胱内注射肉毒杆菌毒素A等二线治疗选择是治疗手段中的宝贵补充，但它们相对具有侵入性，且可能有严重的副作用。1983年首次描述了通过对胫后神经进行外周神经调节来抑制逼尿肌活动，近期的作者进一步证实其阳性反应率为60%-80%。本综述旨在研究关于经皮胫神经刺激的已发表文献，并讨论该技术的结果指标、维持治疗和预后因素。
