Petrasek Danny, Bidner Marissa
California Institute of Technology (Caltech), Los Angeles, CA 90046, USA.
J Diabetes Sci Technol. 2009 May 1;3(3):533-5. doi: 10.1177/193229680900300318.
In 2008, the Action to Control Cardiovascular Risk in Diabetes trial was halted due to an unexpected number of deaths in the intensive treatment group (aiming for hemoglobin A1c levels less than 6%). Hypoglycemic episodes were thought by some to be a contributing cause, underscoring again the challenge of maintaining tight control while avoiding dangerous excursions into hypoglycemic territory. Albisser and colleagues present a set of articles in this issue of Journal of Diabetes Science and Technology that describe a clinical product developed specifically for this timeless clinical conundrum.