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密西西比州的砷暴露:病例回顾

Arsenic exposures in Mississippi: a review of cases.

作者信息

Park M J, Currier M

机构信息

Mississippi State Department of Health, Bureau of Preventive Health Services, Jackson 39215-1700.

出版信息

South Med J. 1991 Apr;84(4):461-4. doi: 10.1097/00007611-199104000-00012.

DOI:10.1097/00007611-199104000-00012
PMID:2014430
Abstract

Arsenic poisonings occur in Mississippi despite public education campaigns to prevent poisonings in the home. We reviewed 44 Mississippi cases of arsenic exposures occurring from January 1986 to May 1990. We compared the epidemiologic differences between unintentional and intentional poisonings. Cases were found and characterized through the two toxicology laboratories and hospital records. Arsenic-based rodenticides were the arsenic source in 23 of the 44 exposures. Other sources were monosodium methylarsenate (4 cases), dodecyl ammonium methane arsonate (5 cases), and other compounds (12 cases). Of the 44 exposures, 27 were unintentional, 7 were suicide attempts, 6 were homicide attempts, and 4 were of unknown intent. Of the 27 unintentionally exposed patients, 19 were black and 14 were male; their median age was 3 years. Of the 13 intentionally poisoned persons, 9 were male and 10 were black, with a median age of 28 years. Six of the seven patients who attempted suicide were white; four of the six victims of attempted homicide were black. We recommend removal of remaining bottles of arsenic-based rodenticides from store shelves, and we urge practicing physicians to warn patients of the dangers of using such rodenticides.

摘要

尽管开展了预防家庭中毒的公众教育活动,但密西西比州仍发生了砷中毒事件。我们回顾了1986年1月至1990年5月间密西西比州发生的44例砷暴露病例。我们比较了非故意中毒和故意中毒之间的流行病学差异。通过两个毒理学实验室和医院记录查找并描述了病例。在44例暴露病例中,有23例的砷源是含砷灭鼠剂。其他来源包括甲基砷酸钠(4例)、十二烷基甲烷磺酸砷(5例)和其他化合物(12例)。在44例暴露病例中,27例为非故意暴露,7例为自杀未遂,6例为杀人未遂,4例意图不明。在27例非故意暴露患者中,19例为黑人,14例为男性;他们的年龄中位数为3岁。在13例故意中毒者中,9例为男性,10例为黑人,年龄中位数为28岁。7例自杀未遂患者中有6例为白人;6例杀人未遂受害者中有4例为黑人。我们建议从商店货架上撤下剩余的含砷灭鼠剂瓶子,并敦促执业医师向患者警告使用此类灭鼠剂的危险。

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