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门诊患者应用环丙沙星与艰难梭菌感染的相关性。

Association of ciprofloxacin prescriptions to outpatients to Clostridium difficile infections.

机构信息

Synlab Medical Care Service, Medical Care Centre Weiden, Weiden, Germany.

出版信息

Euro Surveill. 2010 Feb 4;15(5):19479.

PMID:20144444
Abstract

To study if antibiotic treatment of outpatients had triggered Clostridium difficile infections (CDI), prescription numbers were compared with CDI-affected patient numbers. A strong correlation was observed for ciprofloxacin (R=0.917), suggesting that increased use of ciprofloxacin by outpatients contributed to increased numbers of CDI. These findings deserve further investigation as they may have an impact on future decisions regarding antibiotic prescribing.

摘要

为了研究门诊抗生素治疗是否引发了艰难梭菌感染(CDI),我们比较了处方数量和 CDI 患者数量。环丙沙星(ciprofloxacin)的相关性很强(R=0.917),这表明门诊患者使用环丙沙星的增加导致了 CDI 数量的增加。这些发现值得进一步研究,因为它们可能对未来关于抗生素处方的决策产生影响。

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Seasonal variations in Clostridium difficile infections are associated with influenza and respiratory syncytial virus activity independently of antibiotic prescriptions: a time series analysis in Quebec, Canada.
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Recognition of Clostridium difficile PCR-ribotypes 001, 027 and 126/078 using an extended MALDI-TOF MS system.应用扩展 MALDI-TOF MS 系统识别艰难梭菌 PCR-核糖型 001、027 和 126/078。
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