Faculty of Life Sciences, The University of Manchester, Manchester, UK.
Neurochem Int. 2010 Nov;57(4):332-43. doi: 10.1016/j.neuint.2010.02.002. Epub 2010 Feb 6.
Neuronal-glial networks are the substrate for the brain function. Evolution of the nervous system resulted in the appearance of highly specialized neuronal web optimized for rapid information transfer. This neuronal web is embedded into glial syncytium, thereby creating sophisticated neuronal-glial circuitry were both types of neural cells are working in concert, ensuring amplification of brain computational power. In addition neuroglial cells are fundamental for control of brain homeostasis and they represent the intrinsic brain defence system, being thus intimately involved in pathogenesis of neurological diseases.
神经元-神经胶质网络是大脑功能的基础。神经系统的进化导致了高度专业化的神经元网络的出现，这种网络优化了快速信息传递。这种神经元网络嵌入到神经胶质合胞体中，从而创建了复杂的神经元-神经胶质电路，两种类型的神经细胞协同工作，确保了大脑计算能力的增强。此外，神经胶质细胞对于控制大脑内环境稳态至关重要，它们代表了内在的大脑防御系统，因此密切参与了神经疾病的发病机制。
