Department of Neurology, Apollo Gleneagles Hospitals, 58 Canal Circular Road, Kolkata 700054, India.
J Neurol Neurosurg Psychiatry. 2010 Feb;81(2):154-6. doi: 10.1136/jnnp.2008.160416.
To study the occurrence of utilisation behaviour (UB) in patients with frontotemporal dementia (FTD).
Twenty patients who fulfilled all core Consensus statement criteria for FTD were examined by a neurologist experienced in dementia and by a clinical neuropsychologist. All patients had imaging evidence of predominantly frontal or frontotemporal involvement. Behavioural data were obtained from care givers using a semistructured questionnaire. Questions related to UB were asked in detail. Further assessment for UB was done during the interview with the patient using common objects. Only frank and coherent UB was considered for the study. For comparison, 34 patients with probable Alzheimer's disease diagnosed by the NINCDS-ADRDA criteria were also similarly studied.
80 per cent of our patients with FTD but none with probable Alzheimer's disease exhibited UB. Fourteen out of the 16 patients with FTD who exhibited UB were less than 70 years old. Among patients with UB, 88% exhibited a wide range of 'incidental' UB. Objects of daily use tended to trigger UB most commonly. Utilisation behaviour tended to correspond to premorbid habits in at least 75% of our patients.
Utilisation behaviour may be more common in FTD patients than is currently recognised. The presence of UB should be queried in every patient suspected to be suffering from FTD. A comprehensive questionnaire for UB such as that used here could be useful.
研究额颞叶痴呆（FTD）患者的利用行为（UB）发生情况。
对 20 名符合 FTD 所有核心共识标准的患者进行了神经病学专家和临床神经心理学家的检查。所有患者均有影像学证据显示主要为额部或额颞叶受累。使用半结构化问卷从护理人员处获得行为数据。详细询问与 UB 相关的问题。在与患者面谈时，使用常见物品进一步评估 UB。仅考虑明显和连贯的 UB 进行研究。为了比较，还对 34 名符合 NINCDS-ADRDA 标准的可能患有阿尔茨海默病的患者进行了类似研究。
80%的 FTD 患者表现出 UB，但无一例可能患有阿尔茨海默病的患者。在表现出 UB 的 16 名 FTD 患者中，有 14 名年龄小于 70 岁。在有 UB 的患者中，88%表现出广泛的“偶然”UB。日常使用的物品最容易引发 UB。在我们的至少 75%的患者中，UB 往往与发病前的习惯相对应。
与目前认知相比，UB 在 FTD 患者中可能更为常见。在怀疑患有 FTD 的每个患者中都应该询问 UB 的存在。在这里使用的用于 UB 的全面问卷可能会很有用。
