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Targeted cancer stem cell therapies start with proper identification of the target.

作者信息

Vlashi Erina, Pajonk Frank

出版信息

Mol Cancer Res. 2010 Feb;8(2):291; author reply 291. doi: 10.1158/1541-7786.MCR-09-0505. Epub 2010 Feb 9.

DOI:10.1158/1541-7786.MCR-09-0505
PMID:20145040
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2824786/
Abstract
摘要

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本文引用的文献

1
NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts.NOTCH 通路阻断可耗竭 CD133 阳性脑胶质瘤细胞，并抑制肿瘤神经球和异种移植物的生长。
Stem Cells. 2010 Jan;28(1):5-16. doi: 10.1002/stem.254.
2
z-Leucinyl-leucinyl-norleucinal induces apoptosis of human glioblastoma tumor-initiating cells by proteasome inhibition and mitotic arrest response.z-Leucinyl-leucinyl-norleucinal 通过蛋白酶体抑制和有丝分裂阻滞反应诱导人神经胶质瘤肿瘤起始细胞凋亡。
Mol Cancer Res. 2009 Nov;7(11):1822-34. doi: 10.1158/1541-7786.MCR-09-0225. Epub 2009 Oct 27.
3
In vivo imaging, tracking, and targeting of cancer stem cells.癌症干细胞的体内成像、追踪与靶向
J Natl Cancer Inst. 2009 Mar 4;101(5):350-9. doi: 10.1093/jnci/djn509. Epub 2009 Feb 24.